82985-18-0Relevant academic research and scientific papers
Diastereoselective synthesis of α-methyl and α-hydroxy-β- amino acids via 4-substituted-1,3-oxazinan-6-ones
Sleebs, Brad E.,Hughes, Andrew B.
, p. 3340 - 3352 (2008/02/08)
(Chemical Equation Presented) 1,3-Oxazinan-6-ones have been utilized in a series of enolate reactions to produce 5-hydroxy and 5-alkyl-4-substituted-1,3- oxazinan-6-ones with excellent trans diastereoselectivity. Highlighting the versatility of the oxazin
Tributyltin Cyanide, a Novel Reagent for the Stereoselective Preparation of 3-Amino-2-hydroxy Acids via Cyanohydrin Intermediates
Herranz, Rosario,Castro-Pichel, Julia,Garcia-Lopez, Teresa
, p. 703 - 706 (2007/10/02)
Reaction of tributyltin cyanide with optically active 2-N-benzyloxycarbonylamino aldehydes 1 gives the corresponding O-tributylstannyl cyanohydrins 2 and 3 stereoselectively.Compounds 2 and 3 are transformed in situ into the methyl 3-N-benzyloxycarbonylam
