82985-50-0Relevant academic research and scientific papers
Thermal cleavage of the Fmoc protection group
Hoeck, Stefan,Marti, Roger,Riedl, Rainer,Simeunovic, Marina
experimental part, p. 200 - 202 (2011/08/05)
The Fmoc protection group is among the most commonly used protection groups for the amino function. A fast method for the thermal deavage of this protection group under base-free conditions without the need for dibenzofulvene scavengers is presented. The advantages of this method include straightforward testability by means of a simple high-temperature NMR experiment, usually high yields, and good selectivity towards the BOC protection group and t-butyl ethers.
Total Synthesis of PHI
Moroder, L.,Goehring, W.,Thamm, P.,Wuensch, E.,Tatemoto, K.,et al.
, p. 772 - 780 (2007/10/02)
PHI has recently been isolated from porcine duodenum as a new peptide factor with VIP-like activities.Its primary structure corresponds to a linear heptacosapeptide amide characterized by a remarkable sequence homology to the other known members of the gl
