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Z-(D)-Trp-(D)-Trp(COOH) is a synthetic dipeptide composed of two D-tryptophan (D-Trp) residues, with a carboxylic acid group (COOH) at the end and a benzyloxycarbonyl (Z) protecting group on the N-terminus. Z-(D)-Trp-(D)-Trp(COOH) is often used in peptide synthesis and research, as the D-amino acids provide a chiral center, which can lead to different biological activities compared to their L-amino acid counterparts. The Z group is a temporary protecting group that shields the N-terminus from unwanted side reactions during peptide synthesis, and it can be removed under mild acidic conditions once the desired peptide sequence is achieved. The presence of two tryptophan residues in this dipeptide may also contribute to its potential applications in studying protein-protein interactions or as a building block for more complex peptide structures.

82989-09-1

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82989-09-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 82989-09-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,9,8 and 9 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 82989-09:
(7*8)+(6*2)+(5*9)+(4*8)+(3*9)+(2*0)+(1*9)=181
181 % 10 = 1
So 82989-09-1 is a valid CAS Registry Number.

82989-09-1Downstream Products

82989-09-1Relevant academic research and scientific papers

STEREOSELECTIVITY IN MICELLAR AND VESICULAR REACTIONS

Moss, Robert A.,Taguchi, Takayuki,Bizzigotti, George O.

, p. 1985 - 1988 (1982)

The diastereoselectivity of esterolytic cleavage of certain dipeptide and tripeptide activated esters is lower in thio-functionalized vesicles than in comparable micelles.This is thought to be a mechanism-specific effect related to the greater molecular o

TREATMENT OF PROTEIN FOLDING DISORDERS

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Page/Page column 131, (2010/11/25)

In certain embodiments, the invention is directed to a method for treating a protein folding disorder such as Alzheimer's disease, dementia, Parkinson's disease, Huntington's disease and prion-based spongiform encephalopathy. The method comprises the administration to a subject of a compound of the formula (I) wherein A and B are independently a mono- or bicyclic aromatic group or heteroaromatic cyclic group. In preferred embodiments, the compounds are bis-indole compounds.

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