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2,5-DIAMINO-3-CHLOROBENZONITRILE, also known as DCB, is a chemical compound with the molecular formula C7H5ClN4. It is a white crystalline solid that is commonly used as an intermediate in the synthesis of various pharmaceutical compounds, dyes, and agrochemicals. DCB is known for its high reactivity and versatility, making it a valuable building block for the production of a wide range of organic compounds. This chemical is also used as a precursor in the manufacturing of pigments and polymers. Additionally, DCB has been studied for its potential use as an anti-cancer agent and for its inhibitory effects on certain enzymes. However, it is important to handle this chemical with care, as it can be toxic and harmful if not used properly.

82997-64-6

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82997-64-6 Usage

Uses

Used in Pharmaceutical Industry:
2,5-DIAMINO-3-CHLOROBENZONITRILE is used as an intermediate in the synthesis of various pharmaceutical compounds for its high reactivity and versatility in the production of a wide range of organic compounds.
Used in Dye Industry:
2,5-DIAMINO-3-CHLOROBENZONITRILE is used as an intermediate in the synthesis of dyes for its ability to contribute to the production of a variety of organic compounds.
Used in Agrochemical Industry:
2,5-DIAMINO-3-CHLOROBENZONITRILE is used as an intermediate in the synthesis of agrochemicals for its high reactivity and versatility in the production of a wide range of organic compounds.
Used in Pigment and Polymer Manufacturing:
2,5-DIAMINO-3-CHLOROBENZONITRILE is used as a precursor in the manufacturing of pigments and polymers for its ability to contribute to the production of a variety of organic compounds.
Used in Anti-Cancer Research:
2,5-DIAMINO-3-CHLOROBENZONITRILE is used as a potential anti-cancer agent for its inhibitory effects on certain enzymes and its potential use in cancer treatment.
Used in Enzyme Inhibition Studies:
2,5-DIAMINO-3-CHLOROBENZONITRILE is used in studies for its inhibitory effects on certain enzymes for potential applications in various fields.

Check Digit Verification of cas no

The CAS Registry Mumber 82997-64-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,9,9 and 7 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 82997-64:
(7*8)+(6*2)+(5*9)+(4*9)+(3*7)+(2*6)+(1*4)=186
186 % 10 = 6
So 82997-64-6 is a valid CAS Registry Number.

82997-64-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,5-DIAMINO-3-CHLOROBENZONITRILE

1.2 Other means of identification

Product number -
Other names 2,5-diamino-3-chloro-benzonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:82997-64-6 SDS

82997-64-6Downstream Products

82997-64-6Relevant academic research and scientific papers

Efficient and recyclable bimetallic Co–Cu catalysts for selective hydrogenation of halogenated nitroarenes

Lu, Xionggang,Ren, Jiaan,Sheng, Yao,Wang, Xueguang,Wu, Baoqin,Zou, Xiujing

, (2021/12/20)

Silica supported N-doped carbon layers encapsulating Co–Cu nanoparticles (Co1Cux@CN/SiO2) were prepared by a one-step impregnation of Co(NO3)2·6H2O, Cu(NO3)2·3H2O, urea and glucose, following in situ carbothermal reduction. Effects of Cu contents on the catalytic performance of the Co1Cux@CN/SiO2 catalysts were investigated for selective hydrogenation of p-chloronitrobenzene to p-chloroaniline. The Co1Cu0.30@CN/SiO2 with Cu/Co molar ratio of 0.30:1 presented much higher activity and stability than the monometallic Co@CN/SiO2 catalyst. The addition of Cu into Co1Cux@CN/SiO2 catalysts had favorable effects on the formation of highly active Co–N sites and N-doped carbon layer. The role of the N-doped carbon layer was to protect the Co from oxidation by air, and the Co1Cu0.30@CN/SiO2 could be reused for at least 12 cycles without decrease in catalytic efficiency. Mechanistic and in situ infrared studies revealed that the interaction effect between the Co and Cu atoms made the surface of Co highly electron rich, which decreased adsorption of halogen groups and resulting in the enhanced selectivity during chemoselective hydrogenation of halogenated nitroarenes for a wide scope of substrates.

Preparation of Well-Ordered Mesoporous-Silica-Supported Ruthenium Nanoparticles for Highly Selective Reduction of Functionalized Nitroarenes through Transfer Hydrogenation

Wei, Ning,Zou, Xiujing,Huang, Haigen,Wang, Xueguang,Ding, Weizhong,Lu, Xionggang

supporting information, p. 209 - 214 (2018/01/26)

MCM-41-type mesoporous silica (OMS-IL) was prepared by using an ionic liquid (1-hexadecyl-3-methylimidazolium bromide) as a template. The XRD and TEM results demonstrated that OMS-IL was more stable than the MCM-41 material. Ru nanoparticles were supported on OMS-IL (Ru/OMS-IL) by impregnating OMS-IL with a RuCl3 aqueous solution, and the resulting material was used for the selective reduction of nitroarenes. The effects of the components of the catalysts and the reaction conditions on the catalytic behavior of the prepared catalysts were investigated in detail. Ru/OMS-IL exhibited high catalytic activity and chemoselectivity for the reduction of various substituted nitroarenes to the corresponding aromatic amines in ethanol with hydrazine hydrate as a hydrogen donor under mild conditions. The Ru/OMS-IL catalysts were highly stable and could easily be recovered by simple filtration over at least six recycling reactions without any observable loss in catalytic performance.

N-doped graphitic carbon-improved Co-MoO3 catalysts on ordered mesoporous SBA-15 for chemoselective reduction of nitroarenes

Huang, Haigen,Liang, Xiangcheng,Wang, Xueguang,Sheng, Yao,Chen, Chenju,Zou, Xiujing,Lu, Xionggang

, p. 127 - 137 (2018/05/04)

Metallic Co-MoO3 catalysts supported on ordered mesoporous SBA-15 were first prepared through in situ reaction of SBA-15-supported Co-Mo oxides with 1,10-phenanthroline. The resulting Co-MoO3/NC@SBA-15 catalysts with N-doped carbon (NC) exhibited high catalytic activity and chemoselectivity for selective reduction of various functionalized nitroarenes to the corresponding arylamines in ethanol with hydrazine hydrate at near room temperature (30 °C). For reduction of all tested substrates (28 examples), the catalyst could afford a conversion of >99% and arylamine selectivity of >99%. The excellent catalytic performance of the Co-MoO3/NC@SBA-15 was attributed to the Co-Nχ(C)-Mo active sites generated through the interaction between the surface Co-Nχ(C) and MoO3 species, promoting the dissociation of hydrazine molecule into the active H* species for the reduction of nitro groups. After the seventh cycle for reduction of 4-methoxylnitrobenzene, the 2%Co-MoO3/NC@SBA-15 showed little change in catalytic performance, textural properties, size and dispersion of metal species and valence states of elements, indicating high stability and recyclability.

SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES

-

Page/Page column 42, (2008/06/13)

The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.

The Conjugated N,N'-(Polyenediylidene)bis-sulphenamide Chromophore. Part I. N,N'-Bisarylthio-quinone Diimines

Shand, Charles A.,Thomson, Ronald H.,Greenhalgh, Colin W.

, p. 1601 - 1617 (2007/10/02)

N,N'-Bisarylthio-quinone diimines have been prepared from p-phenylenediamines and arenesulphenyl chlorieds, and from N,N'-dichloroquinone diimines and thiols.They are intensely coloured (the N,N'-dialkyl derivatives also) and exhibit Z/E isomerism in solu

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