83-29-4 Usage
Description
5-(sec-pentyl)barbituric acid, also known as amobarbital, is a barbiturate derivative characterized by its sedative and hypnotic properties. It functions as a central nervous system depressant, enhancing the activity of the neurotransmitter GABA, which leads to a reduction in brain activity and promotes relaxation.
Used in Pharmaceutical Industry:
5-(sec-pentyl)barbituric acid is used as a therapeutic agent for the treatment of anxiety, insomnia, and seizures. Its sedative and hypnotic effects help alleviate these conditions by inducing a state of calm and relaxation.
Used in Pre-Anesthetic Preparation:
5-(sec-pentyl)barbituric acid is used as a pre-anesthetic medication to reduce anxiety and tension in patients before surgery. Its calming effects help patients to cope with the stress associated with surgical procedures.
However, due to its high potential for abuse and addiction, as well as the risks of tolerance, physical dependence, and fatal overdose, 5-(sec-pentyl)barbituric acid is classified as a Schedule II controlled substance in the United States. This classification reflects the need for strict regulation and careful use of the substance in medical settings to ensure patient safety and minimize the potential for misuse.
Check Digit Verification of cas no
The CAS Registry Mumber 83-29-4 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 8 and 3 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 83-29:
(4*8)+(3*3)+(2*2)+(1*9)=54
54 % 10 = 4
So 83-29-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H14N2O3/c1-3-4-5(2)6-7(12)10-9(14)11-8(6)13/h5-6H,3-4H2,1-2H3,(H2,10,11,12,13,14)
83-29-4Relevant articles and documents
Secobarbital artificial antigen and preparation method thereof
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Paragraph 0029; 0063-0065, (2018/09/28)
The objective of the invention is to provide a secobarbital artificial antigen and a preparation method thereof. According to the invention, malonate and urea are used as main raw materials for synthesis of the secobarbital antigen. The method comprises the following steps: reacting halogenated pentane with malonate to prepare 2-(1-methylbutyl)malonate; subjecting a malonate derivative and urea toa cyclization reaction to prepare barbitone derivative; reacting long-chain halogenated olefine acid with the barbitone derivative to prepare a hapten; and reacting the hapten reacts with N-hydroxysuccinimide and N,N-cyclohexylcarbodiimide under nitrogen protection to obtain active ester, subjecting the active ester and a protein to a coupling reaction, and simultaneously removing a trifluoroacetyl protecting group so as to obtain the secobarbital artificial antigen. The preparation method provided by the invention is simple in process, low in production cost, and not limited in raw materialsources. The prepared artificial antigen can be used for animal immunization to obtain corresponding antibodies, is used for the research of various barbitone immunoassays and the production of rapiddetection kits, and has a wide application scope.
Photochemical degradation of barbituric acid derivatives. Part 6: Products of photolysis of 5-allyl-5-(1-methylbutyl)barbituric acid-secobarbital
Barton,Bojarski
, p. 630 - 631 (2007/10/02)
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