830-78-4Relevant academic research and scientific papers
HETEROCYCLIC CARBOXYLATE COMPOUNDS AS GLYCOLATE OXIDASE INHIBITORS
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Page/Page column 105-106, (2021/05/07)
The present disclosure relates generally to modulators of human glycolate oxidase enzyme and methods of use and manufacture thereof. (I)
Fused v-Triazolo-heterocycles. Part 2. Synthesis of 4H-v-Triazolooxadiazin-4-ones from the 1-Aroylamino-v-triazole-5-carboxylic Acids
Rodios, Nestor A.
, p. 1275 - 1279 (2007/10/02)
The synthesis of some 4H-v-triazolooxadiazin-4-ones is described.They are prepared by the reaction of the corresponding 1-aroylamino-v-triazole-5-carboxylic acids with thionyl chloride in the presence of pyridine.The spectroscopic data of th
REACTION OF ACETYLENE NITRILES WITH AZIDES
Vereshchagin, L. I.,Filippova, T. M.,Bol'shedovorskaya, R. L.,Gavrilov, L. D.,Pavlova, G. A.
, p. 128 - 132 (2007/10/02)
The addition of organic and inorganic azides to 3-phenylpropynenitrile and 4-phenyl-2-hydroxy-3-butynenitrile was investigated.It was shown that organic azides add to 3-phenylpropynenitrile exclusively at the triple bond.The reaction with aluminum azide takes place with the participation of the acetylene bond and the nitrile group.The reaction of 4-phenyl-2-hydroxy-3-butynenitrile with azides is accompanied by decomposition to phenylpropargylaldehyde with the subsequent formation of 4-formyl-1,2,3-triazole.The oxidation of 4-phenyl-2-hydroxy-3-butynenitrile withactive manganese dioxide with the simultaneous addition of the azides leads to the formation of 4-carboxy-5-phenyl-1,2,3-triazole.
