830-78-4

Basic information

• Product Name: 5-Phenyl-1H-1,2,3-triazole-4-carboxylic acid
• Synonyms: 5-Phenyl-1H-1,2,3-triazole-4-carboxylic acid
• CAS NO: 830-78-4
• Molecular Formula: C₉H₇N₃O₂
• Molecular Weight: 189.17078
• Mol File: 830-78-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 200-202 °C (decomp)
• Boiling Point: 438.1±25.0 °C(Predicted)
• Appearance: /
• Density: 1.432±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 3.19±0.50(Predicted)
• CAS DataBase Reference: 5-Phenyl-1H-1,2,3-triazole-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Phenyl-1H-1,2,3-triazole-4-carboxylic acid(830-78-4)
• EPA Substance Registry System: 5-Phenyl-1H-1,2,3-triazole-4-carboxylic acid(830-78-4)

Safety Data

• Hazardous Substances Data: 830-78-4(Hazardous Substances Data)

Upstream product

• 51719-84-7 4-formyl-5-phenyl-1,2,3-triazole 
• 637-44-5 phenylpropyolic acid 
• 113631-57-5 4-methoxy-benzoic 4-methoxy-N-(5-methyl-4-phenyl-[1,2,3]triazol-1-yl)-benzimidic anhydride 
• 113631-58-6 C₂₃H₁₆Cl₂N₄O₂ 
• 113631-63-3 4-Phenyl-5-methyl-1-(p-methoxybenzoyl)amino-1,2,3-triazole 
• 113631-65-5 4-Phenyl-5-methyl-1-(o-chlorobenzoyl)amino-1,2,3-triazole 
• 2579-22-8 Phenylpropargyl aldehyde 
• 84452-21-1 2-hydroxy-4-phenyl-3-butynenitrile 

Downstream Products

• 1680-44-0 4-phenyl-1H-1,2,3-triazole 

Relevant articles and documents

HETEROCYCLIC CARBOXYLATE COMPOUNDS AS GLYCOLATE OXIDASE INHIBITORS

The present disclosure relates generally to modulators of human glycolate oxidase enzyme and methods of use and manufacture thereof. (I)

REACTION OF ACETYLENE NITRILES WITH AZIDES

The addition of organic and inorganic azides to 3-phenylpropynenitrile and 4-phenyl-2-hydroxy-3-butynenitrile was investigated.It was shown that organic azides add to 3-phenylpropynenitrile exclusively at the triple bond.The reaction with aluminum azide takes place with the participation of the acetylene bond and the nitrile group.The reaction of 4-phenyl-2-hydroxy-3-butynenitrile with azides is accompanied by decomposition to phenylpropargylaldehyde with the subsequent formation of 4-formyl-1,2,3-triazole.The oxidation of 4-phenyl-2-hydroxy-3-butynenitrile withactive manganese dioxide with the simultaneous addition of the azides leads to the formation of 4-carboxy-5-phenyl-1,2,3-triazole.