83004-43-7

Upstream product

• 3469-00-9 methyl 2,2-diphenylacetate 
• 83004-40-4 2,2-di(4-nitrophenyl)-1,1-dimethoxy-ethene 
• 7697-37-2 nitric acid 

Downstream Products

• 1817-74-9 bis(4-nitrophenyl)methane 
• 119114-18-0 bis-(4-amino-phenyl)-acetic acid methyl ester 
• 3740-55-4 2,2-bis(4-nitrophenyl)ethanoic acid 
• 857224-50-1 2,2-bis-(4-nitro-phenyl)-propionic acid methyl ester 
• 1033-26-7 4,4'-dinitrobenzophenone 
• 611-98-3 4,4'-diaminobenzophenone 
• 17303-16-1 bis(4-azidophenyl)methanone 
• 146509-65-1 bis-(4-amino-phenyl)-acetic acid 
• 89431-04-9 bis-(4-nitro-phenyl)-acetyl chloride 

Relevant academic research and scientific papers

Diphenylmethylene hydroxamic acids as selective class IIa histone deacetylase inhibitors

We have identified a series of diphenylmethylene hydroxamic acids as novel and selective HDAC class IIa inhibitors. The original hit, N-hydroxy-2,2-diphenylacetamide (6), has sub-micromolar class IIa HDAC inhibitory activity, while the rigidified oxygen a

INHIBITORS OF HISTONE DEACETYLASE

This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula compounds of the Formula (I) and N-oxides, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof, and racemic and scalemic mixtures, diastereomers and enantiomers thereof, wherein groups L, M, X and Y are as defined herein.

Models for intramolecular exchange in organic π-conjugated open-shell systems. A comparison of 1,1-ethenediyl and carbonyl linked bis(arylnitrenes)

Linkage of two phenylnitrene electron-spin-bearing units by exchange coupling linker groups leads to model open-shell π-conjugated systems of the general structure :N-Ph-X-Ph-N: of various possible connectivity types. Use of variable-temperature electron

The reinvestigation of the kinetics of the reactions of fluorodi(4-nitrophenyl)ethanes with sodium methoxide in methanol

The procedure previously described for the preparation of 1-fluoro-2,2-di(4-nitrophenyl)ethane actually yields 1,1,2-tri(4-nitrophenyl)ethane.Fluoro-2,2-di(4-nitrophenyl)ethane has been prepared and rate constants, isotope effects, and activation parameters for the β-elimination reaction with methoxide ion in methanol are reported.These parameters indicate a concerted E2 mechanism, with a fairly symmetrical transition state.The subsequent dimerization reaction of the olefin product to yield 1,1,3,3-tetra(4-nitrophenyl)butene-1 is described.The reaction of 1,1,1-trifluoro-2,2-di(4-nitrophenyl)ethane with methoxide ion in methanol has been reinvestigated and the reaction on the first product 1,1-difluoro-2,2-di(4-nitrophenyl)ethylene with excess methoxide, to give di(4-nitrophenyl)ketene dimethylacetal in a multistep reaction, is reported.