83019-42-5

Upstream product

• 75652-71-0 (+)-(3S,5S)-3-allyl-3-ethyl-5-trityloxymethyltetrahydrofuran-2-one 
• 73968-62-4 (5S)-5-[(trityloxy)methyl]tetrahydro-2-furanone 
• 75652-70-9 (+)-(3R,5S)-3-allyl-5-trityloxymethyltetrahydrofuran-2-one 

Relevant academic research and scientific papers

Chiral Synthesis of (+)-Eburnamine, (-)-Eburnamenine, and (-)-Eburnamonine

The (S)-trityl-lactone (6), easily prepared from L-glutamic acid or D-mannitol, has been stereoselectively converted into (+)-eburnamine (3), (-)-eburnamenine (4), and (-)-eburnamonine (2), via the dithiane-lactone (15).

Synthesis of The Chiral Synthon for The Enantioselective Syntheses of The Eburnamine Type Alkaloids

A chiral synthon(5) for the syntheses of the medicinally important indole alkaloid (-)-eburnamonine(10) and the related eburnamine type alkaloids has been prepared in a good yield from the known compound(12) originated from L-glutamic acid or D-mannitol.