83024-75-3Relevant academic research and scientific papers
Effects of Plefin Geometry on the Stereochemistry of Lewis Acid Mediated Additions of Crotylstannanes to Aldehydes
Keck, Gary E.,Savin, Kenneth A.,Cressman, Erik N. K.,Abbott, Duane E.
, p. 7889 - 7896 (2007/10/02)
The role of the double bond geometry (E/Z stereochemistry) in reactions of crotylstannanes with aldehydes has been examined for representative "simple", α-alkoxy, and β-alkoxy aldehydes.For the reaction of crotylstannane with simple achiral aliphatic, aro
STEREOCHEMICAL CONSEQUENCES FOR THE LEWIS ACID MEDIATED ADDITIONS OF ALLYL AND CROTYLTRI-n-BUTYLSTANNANE TO CHIRAL β-HYDROXYALDEHYDE DERIVATIVES
Keck, Gary E.,Abbott, Duain E.
, p. 1883 - 1886 (2007/10/02)
Proper choice of Lewis acid and hydroxyl protecting group allows for selective addition of crotyltri-n-butylstannane to either face of the aldehyde carbonyl in derivatives of 2-methyl-3-hydroxypropanal with preservation of erythro selectivity for the bond
FURTHER STUDIES ON CHROMIUM(II)-MEDIATED HOMOALLYLIC ALCOHOL SYNTHESES
Lewis, Michael D.,Kishi, Yoshito
, p. 2343 - 2346 (2007/10/02)
The stereochemical outcome of chromium(II)-mediated syntheses of homoallylic alcohols has been examined on 11 aldehydes, 3a - 13a.
CROTYLZIRCONIUM DERIVATIVES AS A NEW REAGENT FOR THE THREO SELECTIVE SYNTHESIS OF β-METHYLHOMOALLYL ALCOHOLS
Yamamoto, Yoshinori,Maruyama, Kazuhiro
, p. 2895 - 2898 (2007/10/02)
Crotylzirconium derivatives, prepared from the reaction of crotylmagnesium chloride or crotyllithium with bis(cyclopentadienyl)zirconium dichloride, undergo a rapid reaction with aldehydes to afford the threo product predominantly.The ratio of Cram/anti-Cram product via this reagent is ca. 75/25 ca. 60/40.
