83027-05-8Relevant academic research and scientific papers
Horner Synthesis of Didehydroamino Acid Derivatives in a Liquid-Liquid Two-Phase System
Ciattini, Pier Giuseppe,Morera, Enrico,Ortar, Giorgio
, p. 140 - 142 (2007/10/02)
Horner olefination of aldehydes 1 with N-acyl-2-(diethoxyphosphoryl)glycin ethyl esters 2 to give didehydroamino acid derivatives 3 can be performed advantageously in a 20percent aqueous sodium hydroxide/dichloromethane two-phase system in the absence of any typical phase-transfer catalyst.
