830319-73-8Relevant articles and documents
Double reduction of cyclic aromatic sulfonamides: A novel method for the synthesis of 2- and 3-aryl-substituted cyclic amines
Evans, Paul,McCabe, Thomas,Morgan, Ben S.,Reau, Sophie
, p. 43 - 46 (2007/10/03)
(Chemical Equation Presented) The facile double reduction of bicyclic aromatic sulfonamides was used to synthesize a variety of 2- and 3-aryl-substituted pyrrolidines and 2-phenylpiperidine. The method features a combined nitrogen protection and a traceless tether for the transposition of the aromatic moiety from nitrogen to carbon.