83036-37-7

Upstream product

• 83036-33-3 2-(tert-Butyl-dimethyl-silanyloxymethyl)-4-methyl-5-oxo-3-phenylsulfanyl-cyclopent-3-enecarboxylic acid methyl ester 
• 71847-75-1 methyl (E)-3-lithio-2-methyl-3-phenylthioprop-2-enoate 

Downstream Products

• 83036-38-8 (3aS,6S,6aS)-6-Hydroxy-5,6-dimethyl-4-phenylsulfanyl-3,3a,6,6a-tetrahydro-cyclopenta[c]furan-1-one 

Relevant academic research and scientific papers

SYNTHESIS OF (+/-)-DESEPOXY-4,5-DIDEHYDROMETHYLENOMYCIN A

The reaction of methyl (E)-3-lithio-2-methyl-3-phenylthioprop-2-enoate (4) with methyl (E)-4-(t-butyldimethylsilyloxy)but-2-enoate (5) provides the functionalized cyclopentenone (6) in one step, which is transformed into both Koreeda's and Smith's intermediates (2) and (3) for synthesis of (+/-)-desepoxy-4,5-didehydromethylenomycin A (1).