83039-48-9Relevant academic research and scientific papers
New Leupeptin Analogues: Synthesis and Inhibition Data
McConnell, Rose M.,Barnes, George E.,Hoyng, Charles F.,Gunn, J. Martin
, p. 86 - 93 (2007/10/02)
Syntheses of several tripeptide analogues of leupeptin containing C-terminal argininal, lysinal, or ornithinal units are presented.The synthetic analogues were tested as inhibitors of trypsin, plasmin, and kallikrein. (Benzyloxycarbonyl)-L-leucyl-L-leucyl
L-ARGININAL DERIVATIVES AND A METHOD OF MANUFACTURING THE SAME
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, (2008/06/13)
L-Argininal derivatives of the general formula: STR1 are disclosed. A method of manufacturing any such derivative is also disclosed. The L-argininal derivative of this invention has a strong inhibitory activity on proteases, such as serine and thiol proteases, and is expected to provide useful medicines, including those which are effective for diseases caused by abnormal elevation of protease activity.
