83043-75-8Relevant academic research and scientific papers
12-s-Cis Conformationally Locked 11cis-Retinoids: A Delineation of the Thermal Requirements for -Sigmatropic Shifts and Electrocyclizations in the Vitamin A Series and Novel Spectral Properties
Chandraratna, Roshantha, A. S.,Bayerque, Ann L.,Okamura, William H.
, p. 3588 - 3594 (2007/10/02)
The thermally induced -sigmatropic rearrangement (69 deg C, 4 h) of the six-membered ring fused vinylallenol 5b, a process specific for preparing 11-cis-retinoids, afforded 24 (12percent) and the 12-s-cis-locked retinols 11-cis-7a (14percent), 11-cis
