83058-77-9

Upstream product

• 83009-72-7 6-{3-(tert-Butyl-dimethyl-silanyloxy)-2-[(E)-(S)-3-(tert-butyl-dimethyl-silanyloxy)-3-cyclohexyl-propenyl]-5-oxo-cyclopentylsulfanyl}-2,2-difluoro-hexanoic acid methyl ester 
• 83009-42-1 2,2-Difluoro-6-mercapto-hexanoic acid methyl ester 
• 82476-95-7 (1E)-(3S)-3-tert-butyldimethylsilyloxy-3-cyclohexyl-1-iodo-1-propene 
• 64079-55-6 (R)-4-(tert-Butyldimethylsilanyloxy)-6-oxabicyclo[3.1.0]hexan-2-one 
• 74842-61-8 (+)-(1E)-(3S)-3-cyclohexyl-3-hydroxyl-1-iodo-1-propene 
• 83009-59-0 4(RS)-t-butyldimethylsilyloxy-2-(5,5-difluoro-5-methoxycarbonylpentylthio)-2-cyclopentenone 
• 71399-48-9 3-cyclohexyl-3RS-hydroxy-1-iodoprop-1E-ene 

Relevant academic research and scientific papers

Synthesis of 7-thiaprostaglandin E1 congeners: Potent inhibitors of platelet aggregation

Novel 7-thiaprostaglandin E1 derivatives and congeners were synthesized by a stepwise three-component coupling process, which involves the introduction of α-side chains (thiols) and β-side chains (organocopper reagents) into (R)-4-tert-butyldim