83077-18-3Relevant academic research and scientific papers
Palladium(II)-catalyzed 1,3-dipolar cycloaddition of nitrones with enol ethers
Hori, Kazushige,Ito, Junji,Ohta, Tetsuo,Furukawa, Isao
, p. 12737 - 12744 (2007/10/03)
The 1,3-dipolar cycloadditions of enol ethers as electron-rich olefins with C-phenyl-N-alkyl nitrones proceeded smoothly in the presence of easy handling palladium(II) catalysts under mild conditions to give isoxazolidines in good yield.
Synthesis of 4-alkoxy and 3-nitro substituted isoxazolidines by catalyzed 1,3-dipolar cycloaddition reactions of nitrones with vinyl ethers and nitro alkenes
Meske, Michael
, p. 426 - 433 (2007/10/03)
1,3-Dipolar cycloadditions of the C-phenyl-N-alkylnitrones 1,3 and the C,N-diphenylnitrone (2) with vinyl ethers 5,6 are strongly catalyzed by chiral oxazaborolidines derived from N-arylsulfonyl substituted L-α-amino acids valine and tert-butyl leucine an
1,3-Dipolar cycloaddition reactions of nitrones with alkyl vinyl ethers catalyzed by chiral oxazaborolidines
Seerden, Jean-Paul G.,Boeren, Mike M. M.,Scheeren, Hans W.
, p. 11843 - 11852 (2007/10/03)
The 1,3-dipolar cycloaddition reactions of various Z- and E-nitrones with ethyl vinyl ether and 2,3-dihydrofuran are catalyzed by 20 mol% of chiral oxazaborolidines at room temperature. The effect of high pressure on these reactions is discussed.
Optically Active Tricarbonyl(η6-O-trimethylsilylbenzaldehyde)chromium(0) Complexes in Organic Synthesis: a Highly Diastereoselective 1,3-Dipolar Cycloaddition with Electron-rich Olefins
Mukai, Chisato,Kim, In Jong,Cho, Won Jea,Kido, Masaru,Hanaoka, Miyoji
, p. 2495 - 2504 (2007/10/02)
Heating of a racemic nitrone 2, derived from tricarbonyl(η6-O-trimethylsilylbenzadehyde)chromium(0) complex 1, with electron-rich olefins gave after decomplexation the cis-3,5-disubstituted isoxazolidines in a highly stereo- and regio-selective
Tricarbonyl(benzaldehyde)chromium(0) complexes in organic synthesis: A highly stereoselective 1,3-dipolar cycloaddition of chromium(0)-complexed nitrones
Mukai, Chisato,Cho, Won Jea,Kim, In Jong,Hanaoka, Miyoji
, p. 6893 - 6896 (2007/10/02)
The 1,3-dipolar cycloaddition of chromium(0)-complexed nitrones (10, 11) with electron-rich olefins (2) provided, after decomplexation with CAN, cis-3,5-disubstituted isoxazolidines (cis-14, 15) in a highly stereoselective as well as regioselective manner
Reactions at High Pressures. Dipolar Cycloaddition of Nitrones with Vinyl Ethers
Dicken, Carl Michael,DeShong, Philip
, p. 2047 - 2051 (2007/10/02)
The dipolar cycloaddition of a nitrone and an electron-rich depolarophile can be induced by high-pressure as well as by thermal reaction conditions, and the high-pressure conditions lead to altered stereoselectivities in the cycloaddition.
Determination of Configuration and Conformation of Isoxazolidines by Nuclear Overhauser Effect Difference Spectroscopy
DeShong, Philip,Dicken, C. Michael,Staib, Ronald R.,Freyer, Alan J.,Weinreb, Steven M.
, p. 4397 - 4403 (2007/10/02)
The configurations of isoxazolidines 2, 3, 5, 7, and 10-12 have been assigned by analysis of NMR coupling constants and by nuclear Overhauser effect difference spectroscopy (NOEDS).The preferred solution conformations of isoxazolidines 3 and 5 were determined to be as in 3A/5A.It is proposed that these conformations are adopted to take advantage of the anomeric effect and to alleviate the unfavorable stereoelectronic lone pair-lone pair interaction in the N-O portion of the molecule (gauche effect).
