831-50-5

Basic information

• Product Name: 1-chloro-4-nitro-2-(trichloromethyl)benzene
• Synonyms: 1-chloro-4-nitro-2-(trichloromethyl)benzene
• CAS NO: 831-50-5
• Molecular Weight: 274.918
• Mol File: 831-50-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-chloro-4-nitro-2-(trichloromethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-4-nitro-2-(trichloromethyl)benzene(831-50-5)
• EPA Substance Registry System: 1-chloro-4-nitro-2-(trichloromethyl)benzene(831-50-5)

Safety Data

• Hazardous Substances Data: 831-50-5(Hazardous Substances Data)

Upstream product

• 2136-89-2 2-chlorobenzotrichloride 

Downstream Products

• 2516-96-3 2-chloro-5-nitrobenzoic acid 
• 1252576-51-4 (+/-)-(2E)-3-{2-chloro-4-[cyano(phenyl)methyl]-5-nitrophenyl}-2-phenylacrylonitrile 
• 1252576-53-6 (+/-)-isopropyl (2E)-3-[2-chloro-4-(2-isopropoxy-2-oxo-1-phenylethyl)-5-nitrophenyl]-2-phenylacrylate 
• 71195-69-2 2-Chlor-5-amino-benzotrichlorid 

Relevant articles and documents

Preparation method of 2-chloride-5-nitrobenzoic acid

The invention provides a preparation method of 2-chloride-5-nitrobenzoic acid. The preparation method comprises the following steps: mixing concentrated nitric acid and fuming sulphuric acid with the SO3 concentration of 20 percent according to the mass ratio of 1:(2-3), and controlling the temperature of the solution to be less than 10 DEG C in a mixing process; dripping 2-chloride trichlorotoluene, controlling the temperature of reaction liquid to be 0 to 10 DEG C, and continuously stirring at the end of dripping till the reaction is completed; pouring the reaction liquid into ice water, extracting with dichloromethane, washing an organic phase with a saturated sodium bicarbonate solution, and concentrating and drying to obtain 2-chloride-5-nitro trichlorotoluene; preparing concentrated sulfuric acid with the concentration of 85 weight percent, heating to 60 to 65 DEG C, adding the 2-chloride-5-nitro trichlorotoluene in batches, and preserving the heat till the reaction is completed; cooling the reaction liquid, adding water into the reaction liquid for dilution, extracting with ethyl acetate, taking an organic phase, and performing washing and concentration to obtain 2-chloride-5-nitrobenzoic acid. The technological steps are more reasonable in design and high in operability; the number of byproducts is small; the prepared product is relatively high in purity and can meet the requirement on industrial application.