83104-86-3

Usage

Uses

Used in Pharmaceutical Industry:
(-)-ECG-3''-O-ME is used as a therapeutic agent for its potential health benefits in treating cardiovascular disease, neurodegenerative disorders, and cancer. Its antioxidative, anti-inflammatory, and neuroprotective properties make it a promising candidate for developing novel treatments and preventive measures against these conditions.
Used in Food Industry:
(-)-ECG-3''-O-ME is used as a functional ingredient in food products for its health-promoting effects. Its antioxidative properties can help preserve the freshness and quality of food items, while its potential health benefits can enhance the nutritional value of these products.
Used in Cosmetic Industry:
(-)-ECG-3''-O-ME is used as an active ingredient in cosmetic products for its potential skin health benefits. Its antioxidative and anti-inflammatory properties can contribute to skin protection, repair, and rejuvenation, making it a valuable component in skincare formulations.

Upstream product

• 1186527-21-8 (2R,3R)-2-(3,4-bis(2-nitrophenylsulfonyloxy)phenyl)-5,7-bis(2-nitrophenylsulfonyloxy)-chroman-3-yl 3-methoxy-4,5-bis(2-nitrophenylsulfonyloxy)benzoate 
• 1186527-10-5 4,5-di(2-nitrobenzenesulfonyloxy)-3-methoxybenzoic acid 
• 1186527-20-7 (2R,3R)-2-(3,4-bis(2-nitrophenylsulfonyloxy)phenyl)-3-hydroxychromane-5,7-diyl bis(2-nitrobenzenesulfonate) 
• 70845-74-8 3,4-bis(benzyloxy)-5-methoxybenzoyl chloride 
• 70845-73-7 3,4-bis(benzyloxy)-5-methoxybenzoic acid 

Relevant academic research and scientific papers

Syntheses of methylated catechins and theaflavins using 2-nitrobenzenesulfonyl group to protect and deactivate phenol

An efficient and versatile synthetic method for labile polyphenols was established using 2-nitrobenzenesulfonate (Ns) as a protecting group for phenol. This methodology provides regio-and stereoselective access to a range of methylated catechins, such as methylated epigallocatechin gallates, that are not readily available from natural sources. In addition, biomimetic synthesis of theaflavins from catechins was accomplished using Ns protection to minimize undesired side reactions of electron-rich aromatic rings during oxidation, enabling construction of the complex benzotropolone core in a single-step oxidative coupling reaction. Availability of these compounds will aid detailed structure-biological activity relationship studies of catechins.

Regioselective synthesis of methylated epigallocatechin gallate via nitrobenzenesulfonyl (Ns) protecting group

Regioselective synthesis of methylated epigallocatechin gallate from epigallocatechin was accomplished using a 2-nitrobenzenesulfonyl (Ns) group as a protecting group for phenols. This methodology provided several methylated catechins, which are naturally

Regiospecific and enantioselective synthesis of methylated metabolites of tea catechins

The regiospecific and enantioselective syntheses of various methylated regioisomers of epicatechin gallate (EGC) and epigallocatechin gallate (EGCG) have been achieved.