83119-44-2Relevant academic research and scientific papers
thien-5-yl)oxy>acetic Acids and 1,1-Dioxides. 1. A Structurally Novel Class of Diuretics with Hypotensive Activity
Ong, Helen H.,Caldwell, Steven R.,Profitt, James A.,Tegeler, John J.,Agnew, Marc N.,et al.
, p. 2295 - 2303 (2007/10/02)
A series of thien-5-yl)oxy>acetic acids and their corresponding 1,1-dioxides were synthesized and evaluated for diuretic activity in the acute saline loaded mice (ASLM) and hypotensive activity in the spontaneously hypertensive rat (
Benzo[b]thiophenes
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, (2008/06/13)
Novel benzo[b]thiophenes, compositions containing same, process for the preparation thereof and methods of reducing blood pressure and producing diuresis by administration of the compounds and compositions are disclosed.
Synthesis of (dihydrobenzoxathiinyloxy)acetic acids
Tegeler,Ong,Profitt
, p. 867 - 870 (2007/10/02)
Several (dihydrobenzoxathiinyloxy)acetic acids have been prepared as potential antihypertensive agents. The dihydrobenzoxathiin ring system was constructed via an intramolecular alkoxide displacement reaction.
