83120-05-2Relevant articles and documents
thien-5-yl)oxy>acetic Acids and 1,1-Dioxides. 1. A Structurally Novel Class of Diuretics with Hypotensive Activity
Ong, Helen H.,Caldwell, Steven R.,Profitt, James A.,Tegeler, John J.,Agnew, Marc N.,et al.
, p. 2295 - 2303 (2007/10/02)
A series of thien-5-yl)oxy>acetic acids and their corresponding 1,1-dioxides were synthesized and evaluated for diuretic activity in the acute saline loaded mice (ASLM) and hypotensive activity in the spontaneously hypertensive rat (
Benzo[b]thiophenes
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, (2008/06/13)
Novel benzo[b]thiophenes, compositions containing same, process for the preparation thereof and methods of reducing blood pressure and producing diuresis by administration of the compounds and compositions are disclosed.