831203-31-7Relevant academic research and scientific papers
Synthesis and structure-activity relationship studies of highly potent novel oxazolidinone antibacterials
Komine, Takashi,Kojima, Akihiko,Asahina, Yoshikazu,Saito, Tatsuhiro,Takano, Hisashi,Shibue, Taku,Fukuda, Yasumichi
supporting information; experimental part, p. 6558 - 6562 (2009/10/23)
Novel antibacterial biaryl oxazolidinones bearing an aza-, an oxa-, or a thiabicyclo[3.1.0]hex-6-yl ring system were synthesized, and their in vitro antibacterial activity and structure-activity relationships (SAR) were evaluated. Most of the synthesized
OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS
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Page/Page column 87-88, (2010/10/20)
The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria, for example, multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms, for example, Bacterioides spp. and Clostridia spp. species, and acid fast organisms, for example, Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.
