83131-08-2

Upstream product

• 72517-15-8 2,3-dihydroxy-5-bromobenzoic acid 
• 77-78-1 dimethyl sulfate 
• 303-38-8 2,3-Dihydroxybenzoic acid 

Downstream Products

• 130880-38-5 5-bromo-2,3-dimethoxy-N-(1-benzyl-4-piperidinyl)benzamide 
• 72517-23-8 5-bromo-2,3-dimethoxybenzoic acid 
• 107188-91-0 5-bromo-2,3-dimethoxybenzoic acid chloride 
• 134419-42-4 5-iodo-2,3-dimethoxybenzoic acid 
• 259814-04-5 3-methyloxetane-3-methyl 2,3-dimethoxy-5-bromobenzoate 
• 259814-05-6 1-(2,3-dimethoxy-5-bromo)phenyl-4-methyl-2,6,7-trioxabicyclo[2.2.2]octane 
• 1404548-73-7 ethyl (5-bromo-2,3-dimethoxyphenyl)carbamate 
• 1404548-74-8 5-bromo-2,3-dimethoxyaniline 
• 1404548-78-2 5-[(5-bromo-2,3-dimethoxyphenylamino)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 1404548-86-2 2,3-dimethoxy-5-[(trimethylsilyl)ethynyl]aniline 
• 1404548-88-4 5-[(2,3-dimethoxy-5-(trimethylsilylethynyl)phenylamino)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 1404548-97-5 benzyl (5-bromo-7,8-dimethoxyquinolin-4-yl)carbonate 
• 1404549-00-3 benzyl [7,8-dimethoxy-5-((trimethylsilyl)ethynyl)quinolin-4-yl]carbonate 

Relevant academic research and scientific papers

Synthesis of two unnatural oxygenated aaptaminoids

Two unprecedented oxygenated aaptaminoids have been synthesized starting from cheap and easily available 2,3-dihydroxybenzoic acid with the satisfactory overall yields of 31% and 34%. The key step of the procedure is the divergent thermic 5-exodig vs base

Structure-activity relationship studies of N-(9-benzyl)-9- azabicyclo[3.3.1]nonan-3-β-yl benzamide analogues for dopamine D2 and D3 receptors

A series of benzamide derivatives were prepared in order to determine the nature of the substituent effects in the benzamide aromatic ring on the affinity to dopamine D2 and D3 receptors. Both quantitative structure- activity relatio