83141-11-1

Usage

Uses

Used in Pharmaceutical Industry:
3-Amino-2,6-difluorobenzoic acid is used as a key intermediate in the synthesis of various pharmaceuticals, including antimalarial and anticancer drugs. Its unique chemical structure allows for the development of novel therapeutic agents with improved efficacy and selectivity.
Used in Organic Synthesis:
In the field of organic synthesis, 3-Amino-2,6-difluorobenzoic acid serves as a valuable building block for the creation of a wide range of functional materials. Its presence of fluorine atoms and an amino group enables the formation of diverse chemical entities with specific properties and applications.
Used in Material Science:
3-Amino-2,6-difluorobenzoic acid has potential applications in the development of new materials and technologies due to its unique chemical structure. Its properties make it a promising candidate for the production of advanced materials with tailored characteristics for various industries, such as electronics, coatings, and polymers.

InChI:InChI=1/C7H5F2NO2/c8-3-1-2-4(10)6(9)5(3)7(11)12/h1-2H,10H2,(H,11,12)

Upstream product

• 110-91-8 morpholine 
• 83141-10-0 2,6-difluoro-3-nitrobenzoic acid 
• 7440-06-4 platinum 
• 385-00-2 2,6-difluorobenzoic acid 

Relevant academic research and scientific papers

Development of nematic and orthogonal smectic phases in short-core fluorinated hockey-stick shaped liquid crystal compounds

Here we report synthesis and investigations on novel short-core hockey-stick shaped molecules bearing a 4-n-alkyloxy-2-hydroxybenzylidene moiety at one end and polar fluoro-biphenyl moiety at the other end. The polar chloro and fluoro substituent at the lateral position of the core confers nematic and orthogonal smectic mesomorphism. The mesophase morphology is characterized by polarizing optical microscopy (POM), differential scanning calorimetry (DSC), X-ray diffraction (XRD), electro-optical study and dielectric spectroscopy. The fluorinated compounds 1b (n = 16) and 1c (n = 18) have long terminal hydrocarbon tail and show orthogonal smectic phases with antiferroelectric switching behaviour. The chlorinated compound 2e (n = 8) with relatively short terminal chain length exhibits only a monotropic nematic phase on cooling. The nematic phase is comprised of cybotactic clusters as confirmed by XRD and exhibits electro-optic switching. The compound 2i (n = 12) manifests a short range enantiotropic nematic and additional orthogonal smectic phase. Dielectric spectroscopy reveals polar correlations in the nematic and smectic phases.

A facile approach to the synthesis of 3-(6-Chloro-thiazolo[5,4-b]pyridin-2- ylmethoxy)-2,6-difluoro-benzamide (PC190723)

Practical synthesis of PC 190723, a bacterial cell division protein Ftsz inhibitor, has been achieved in a high overall yield of 45% in six steps from commercially available starting materials. Georg Thieme Verlag Stuttgart · New York.

AMIDE DERIVATIVE AND PESTICIDE CONTAINING SUCH COMPOUND

Disclosed is a compound having high pesticidal effects which is represented by the general formula (1) below. Also disclosed is a pesticide containing such a compound as an active ingredient. (1) (In the formula, A1, A2, A3 and A4 respectively represent a carbon atom or the like; R1 and R2 respectively represents a hydrogen atom or the like; G1 and G2 respectively represents an oxygen atom or the like; X represents a hydrogen atom, a halogen atom or the like; n represents an integer of 0-4; Q1 represents a substituted phenyl group, a substituted heterocyclic group or the like; and Q2 represents a substituted phenyl group, a substituted heterocyclic group or the like.)

3-(Pyrrol-1-yl)phenylmethyl esters and intermediates

3-(Pyrrol-1-yl)phenylmethyl esters and intermediates having the general formula STR1 the use of the esters as pesticides, compositions thereof and a process for preparation are disclosed and exemplified.