83148-91-8 Usage
Description
One of a number of minor alkaloids isolated from Leontice albertii Rgl., this
base crystallizes from petroleum ether as colourless prisms. It is dextrorotatory
having a specific rotation of [α]D + 59.3° (c 1.3, EtOH) and yields a crystalline
methiodide, m.p. 249°C. The structure has been assigned on the basis of chemical
analysis and spectroscopic determinations.
Uses
(+)-Sophoridine acts as an anti-inflammatory agent in vitro and in vivo. Anticancer agent, with a promising anti-tumor effect and lower toxicity.
References
Kamalitdinov, Iskandarov, Yunusov, Khim. Prir. Soedin., 3, 352 (1967) Kamalitdinov, Iskandarov, Yunusov, ibid, 5,409 (1969)
Check Digit Verification of cas no
The CAS Registry Mumber 83148-91-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,1,4 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 83148-91:
(7*8)+(6*3)+(5*1)+(4*4)+(3*8)+(2*9)+(1*1)=138
138 % 10 = 8
So 83148-91-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12-,13-,15+/m1/s1
83148-91-8Relevant articles and documents
Synthesis and biological evaluation of nitric oxide-releasing matrine derivatives as anticancer agents
He, Li Qin,Liu, Jing,Yin, Deng Ke,Zhang, Yi Hua,Wang, Xiao Shan
scheme or table, p. 381 - 384 (2010/12/25)
A series of furoxan-based nitric oxide-releasing matrine derivatives (10a-f) were synthesized. The biological evaluation showed that compounds 10a, 10b, 10e and 10f had stronger cytotoxic activities than 5-fluorouracil against human hepatoma cells (HepG2) in vitro.
