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Sophoridine is a minor alkaloid isolated from Leontice albertii Rgl., crystallizing as colorless prisms from petroleum ether. It is dextrorotatory with a specific rotation of [α]D + 59.3° (c 1.3, EtOH) and forms a crystalline methiodide with a melting point of 249°C. Its structure has been determined through chemical analysis and spectroscopic methods.

83148-91-8

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83148-91-8 Usage

Uses

Used in Pharmaceutical Industry:
Sophoridine is used as an anti-inflammatory agent for its in vitro and in vivo anti-inflammatory effects.
Used in Anticancer Applications:
Sophoridine is used as an anticancer agent, exhibiting promising anti-tumor effects with lower toxicity compared to other agents.

References

Kamalitdinov, Iskandarov, Yunusov, Khim. Prir. Soedin., 3, 352 (1967) Kamalitdinov, Iskandarov, Yunusov, ibid, 5,409 (1969)

Check Digit Verification of cas no

The CAS Registry Mumber 83148-91-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,1,4 and 8 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 83148-91:
(7*8)+(6*3)+(5*1)+(4*4)+(3*8)+(2*9)+(1*1)=138
138 % 10 = 8
So 83148-91-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12-,13-,15+/m1/s1

83148-91-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Sophoridine

1.2 Other means of identification

Product number -
Other names matridin-15-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:83148-91-8 SDS

83148-91-8Relevant academic research and scientific papers

Synthesis and biological evaluation of nitric oxide-releasing matrine derivatives as anticancer agents

He, Li Qin,Liu, Jing,Yin, Deng Ke,Zhang, Yi Hua,Wang, Xiao Shan

scheme or table, p. 381 - 384 (2010/12/25)

A series of furoxan-based nitric oxide-releasing matrine derivatives (10a-f) were synthesized. The biological evaluation showed that compounds 10a, 10b, 10e and 10f had stronger cytotoxic activities than 5-fluorouracil against human hepatoma cells (HepG2) in vitro.

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