83150-77-0Relevant articles and documents
Method for preparing 1-poxlene -8-thiol
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Paragraph 0039-0103, (2019/06/27)
The invention belongs to the technical field of fine chemistry, and provides a method for preparing 1-poxlene-8-thiol, wherein a-terpineol is used as a raw material, and the a-terpineol reacts with athioreagent to obtain the 1-poxlene -8-thiol, the method comprises the following steps: dissolving the a-terpineol in an organic solvent; adding the thioreagent in batches to carry out a thioreaction;the system after reaction is cooled to room temperature, the solvent is removed through rotating evaporation, and sodium hydroxide aqueous solution is slowly added until the pH value is more than orequal to 12; extracting the water phase with methyl tert-ether twice, combining the organic phase, washing with saturated brine once, drying with anhydrous sodium sulfate, concentrating, and distilling under reduced pressure to obtain the product 1-poxlene-8-thiol. The method solves the problems that in the prior art, the synthesis route of the 1-poxlene-8-thiol is complex, the lithium aluminum tetrahydrate in the raw material is expensive, the danger is high, and the prior method is not suitable for industrial production.
Synthesis process method of p-menon-1-ene-8-thiol
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Paragraph 0017; 0019; 0020; 0022; 0023; 0025; 0026; 0028, (2019/04/26)
The invention discloses a synthesis process method of p-menon-1-ene-8-thiol, in particular to a novel synthesis process method for obtaining p-menon-1-ene-8-thiol by using cheap synthetic perfume alpha-terpineol obtained from turpentine oil as a raw material to be reacted with thioacetic acid and then adopting LiAlH4 for reduction. The synthesis process method has the advantages that the synthesisroute is short, the process operation is simple, raw materials and reagents are easy to obtain and cheap, the first reaction cycle is shortened, the yield is high, and more importantly, the cost is greatly reduced.
Simple synthetic protocols for tertiary alkyl and allyl thiols
Gurudutt, K. N.,Rao, Sanjay,Srinivas, P.,Srinivas, S.
, p. 1169 - 1171 (2007/10/03)
Convenient preparative methods for tertiary alkyl and allyl thiols are described. Accordingly, thiolesters and thiocyanates, obtained from the reaction of SN1-active halides and appropriate zinc salts, on hydrolysis and LAH reduction respectively, afford the corresponding thiols in near quantitative yields. Besides the well known p-menth-1-ene-8-thiol, p-menthane-1-thiol, p-mentha-1,8-diene-6-thiol and 2-(2-phenyl)propane thiol have been prepared.