83150-78-1Relevant articles and documents
Synthesis process of isothiocineole
-
Paragraph 0022; 0033; 0038-0039; 0042; 0047-0048; 0051; 0056, (2019/10/23)
The invention discloses a synthesis process of isothiocineole, and relates to the technical field of synthesis of isothiocineole. Alpha-terpineol is taken as an initial raw material, and is sequentially subjected to halogenation reaction, nucleophilic substitution reaction, elimination reaction and Michael addition reaction to prepare a crude isothiocineole product, and the crude isothiocineole product is rectified to obtain a pure isothiocineole product. The synthesis process has the advantages of high yield, low cost, simple operation, suitability for industrial production and the like.
Synthesis process method of p-menon-1-ene-8-thiol
-
Paragraph 0017; 0019; 0020; 0022; 0023; 0025; 0026; 0028, (2019/04/26)
The invention discloses a synthesis process method of p-menon-1-ene-8-thiol, in particular to a novel synthesis process method for obtaining p-menon-1-ene-8-thiol by using cheap synthetic perfume alpha-terpineol obtained from turpentine oil as a raw material to be reacted with thioacetic acid and then adopting LiAlH4 for reduction. The synthesis process method has the advantages that the synthesisroute is short, the process operation is simple, raw materials and reagents are easy to obtain and cheap, the first reaction cycle is shortened, the yield is high, and more importantly, the cost is greatly reduced.
Simple synthetic protocols for tertiary alkyl and allyl thiols
Gurudutt, K. N.,Rao, Sanjay,Srinivas, P.,Srinivas, S.
, p. 1169 - 1171 (2007/10/03)
Convenient preparative methods for tertiary alkyl and allyl thiols are described. Accordingly, thiolesters and thiocyanates, obtained from the reaction of SN1-active halides and appropriate zinc salts, on hydrolysis and LAH reduction respectively, afford the corresponding thiols in near quantitative yields. Besides the well known p-menth-1-ene-8-thiol, p-menthane-1-thiol, p-mentha-1,8-diene-6-thiol and 2-(2-phenyl)propane thiol have been prepared.