83188-08-3

Usage

Uses

Used in Organic Synthesis:
6-Nitroheptan-3-one is utilized as a building block in organic synthesis, playing a crucial role in the creation of various complex organic molecules.
Used in Pharmaceutical Production:
6-Nitroheptan-3-one serves as an essential intermediate in the production of pharmaceuticals, contributing to the development of new drugs and medicines.
Used in Agrochemicals:
6-Nitroheptan-3-one is also used in the synthesis of agrochemicals, aiding in the development of products for agricultural applications.
Used in Flavoring Agents:
Due to its distinctive odor, 6-Nitroheptan-3-one is employed as a flavoring agent in the food and beverage industry, enhancing the taste and aroma of various products.
Used in Antimicrobial Applications:
6-Nitroheptan-3-one has been studied for its potential antimicrobial properties, indicating its possible use in applications that require the inhibition of microbial growth.
Used in Industrial Applications:
6-Nitroheptan-3-one is being investigated for various industrial applications, suggesting its versatility and potential for future use in a range of industries.

Upstream product

• 79-24-3 Nitroethane 
• 33279-05-9 N,N-diethyl-1-amino-3-pentanone 
• 50-00-0 formaldehyd 
• 78-93-3 butanone 
• 1629-58-9 4-penten-3-one 

Downstream Products

• 1703-51-1 heptane-2,5-dione 

Relevant academic research and scientific papers

Ionic liquids made with dimethyl carbonate: Solvents as well as boosted basic catalysts for the michael reaction

This article describes 1) a methodology for the green synthesis of a class of methylammonium and methylphosphonium ionic liquids (ILs), 2) how to tune their acid-base properties by anion exchange, 3) complete neat-phase NMR spectroscopic characterisation

Bifunctional heterogeneous catalysis of silica-alumina-supported tertiary amines with controlled acid-base interactions for efficient 1,4-addition reactions

We report the first tunable bifunctional surface of silica-aluminasupported tertiary amines (SA-NEt2) active for catalytic 1,4-addition reactions of nitroalkanes and thiols to electron-deficient alkenes. The 1,4-addition reaction of nitroalkanes to electron-deficient alkenes is one of the most useful carbon-carbon bond-forming reactions and applicable toward a wide range of organic syntheses. The reaction between nitroethane and methyl vinyl ketone scarcely proceeded with either SA or homogeneous amines, and a mixture of SA and amines showed very low catalytic activity. In addition, undesirable side reactions occurred in the case of a strong base like sodium ethoxide employed as a catalytic reagent. Only the present SA-supported amine (SA-NEt2) catalyst enabled selective formation of a double-alkylated product without promotions of side reactions such as an intramolecular cyclization reaction. The heterogeneous SA-NEt2 catalyst was easily recovered from the reaction mixture by simple filtration and reusable with retention of its catalytic activity and selectivity. Fur-thermore, the SA-NEt2 catalyst system was applicable to the addition reaction of other nitroalkanes and thiols to various electron-deficient alkenes. The solid-state magic-angle spinning (MAS) NMR spectroscopic analyses, including variable-contact-time 13C cross-polarization (CP)/MAS NMR spectroscopy, revealed that acid-base interactions between surface acid sites and immobilized amines can be controlled by pretreatment of SA at different temperatures. The catalytic activities for these addition reactions were strongly affected by the surface acid-base interactions. 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

The Michael reaction of nitroalkanes with conjugated enones in aqueous media

The Michael reaction of various nitroalkanes with conjugated enones can be performed in NaOH 0.025 M and in the presence of cetyltrimethylammonium chloride (CTACl) as cationic surfactant, without any organic solvent. Good yields of the products are obtained even with hindered starting materials.

The Synthesis of 1,4-Diketones via Fluoride-catalysed Michael Addition and Supported-permanganate-promoted Nef Transformation

A versatile synthetic route for the preparation of 1,4-diketones from simple starting materials is described and applied to the preparation of a wide range of diketones.The two most important steps in the reaction are the fluoride ion-catalysed Michael addition of a nitroalkane to a vinyl ketone and the subsequent transformation of the nitro ketone to the diketone using supported permanganate as the oxidant.The interaction of F- with nitroethane has been studied and a number of sources of F- have been tested in the Michael addition reaction.Potassium fluoride supported on alumina and potassium permanganate supported on silica gel are remarkably efficient reagents for the Michael addition and Nef transformation stages, respectively, although it is important to determine the best reagent loadings and drying conditions for maximum reaction efficiency to be achieved.

Synthesis of 1,4-Diketones by Fluoride-catalysed Michael Addition and Supported Permanganate Oxidation

A wide variety of 1,4-diketones may be prepared from simple starting materials by using fluoride ion-catalysed Michael additions and silica gel-supported permanganate-promoted Nef transformations.