83215-18-3

Upstream product

• 110392-56-8 bis(4-nitrobenzyl)phenylamine 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 62-53-3 aniline 
• 24007-66-7 N-(4-aminobenzyl)aniline 

Downstream Products

• 1252602-02-0 N-(methoxycarbonyl)-3-methyl-L-valyl-N-[4-({phenyl[4-({1-[(2R)-2-phenyl-2-pyrrolidin-1-ylacetyl]-L-prolyl}amino)benzyl]amino}methyl)phenyl]-L-prolinamide 
• 1252602-31-5 methyl R-2-oxo-1-phenyl-2-((S)-2-(4-((phenyl(4-((S)-pyrrolidine-2-carboxamido)benzyl)amino)methyl)phenylcarbamoyl)pyrrolidin-1yl)ethylcarbamate 
• 1252600-83-1 methyl (S)-1-((S)-2-(4-(((4-((S)-1-((R)-2-(dimethylamino)-2-phenylacetyl)pyrrolidine-2-carboxamido)benzyl)(phenyl)amino)methyl)phenylcarbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-ylcarbamate 
• 1252600-84-2 methyl (S)-3,3-dimethyl-1-oxo-1-((S)-2-(4-((phenyl(4-((S)-pyrrolidine-2-carboxamido)benzyl)amino)methyl)phenylcarbamoyl)pyrrolidin-1-yl)butan-2-ylcarbamate 
• 1252600-86-4 methyl (S)-1-((S)-2-(4-(((4-((S)-1-((R)-2-(diethylamino)-2-phenylacetyl)pyrrolidine-2-carboxamido)benzyl)(phenyl)amino)methyl)phenylcarbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-ylcarbamate 

Relevant academic research and scientific papers

ANTI-VIRAL COMPOUNDS

Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.

Anti-Viral Compounds

Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.

TRINUCLEAR INTERMEDIATES IN ANILINE-FORMALDEHYDE CONDENSATION

The trinuclear intermediate products 4-(4-anilinomethylanilinomethyl)aniline and 4-aniline were isolated and identified by TLC during investigation of the aniline-formaldehyde condensation in the presence of acidic catalysts.The transformation of these compounds and of 4-anilinomethylaniline in methanol and under the conditions of acid aniline-formaldehyde condensation and rearrangement are described.It was established that the fromation of polyamines is possible not only as a result of the initial reaction of the final diamines with formaldehyde but also of the reaction of protonated anilinomethylanilines with aromatic amines present in the reaction mixture.