83221-68-5Relevant academic research and scientific papers
Enantiomeric synthesis of D- and L-cyclopentenyl nucleosides and their antiviral activity against HIV and West Nile virus
Song,Paul,Choo,Morrey,Sidwell,Schinazi,Chu
, p. 3985 - 3993 (2007/10/03)
Enantiomeric synthesis of D- and L-cyclopentenyl nucleosides and their antiviral activity against HIV and West Nile virus are described. The key intermediate (-)- and (+)-cyclopentenyl alcohols (7 and 15) were prepared from D-γ-ribonolactone and D-ribose,
Cyclopentenylcytosine. A Carbocyclic Nucleoside with Antitumor and Antiviral Properties
Marquez, Victor E.,Lim, Mu-Ill,Treanor, Susan P.,Plowman, Jacqueline,Priest, Matthew A.,et al.
, p. 1687 - 1694 (2007/10/02)
Cyclopentenylcytosine (CPE-C, 2), a pyrimidine analogue of the fermentation derived carbocyclic nucleoside neplanocin A, has been synthesized from the optically active cyclopentenylamine 3b by two synthetic routes.CPE-C demonstrates significant antitumor
ENANTIOSELECTIVE SYNTHESIS OF NEW ANALOGS OF NEPLANOCIN A AND THEIR BIOLOGICAL ACTIVITY
Arita, Masafumi,Okumoto, Takeki,Saito, Tadamasa,Hoshino, Yukio,Fukukawa, Kiyofumi,et al.
, p. 233 - 258 (2007/10/02)
Various carbocyclic nucleosides analogs of neplanocin A (such as 5-aminoimidazole-4-carboxamide riboside, uridine, 5-iodouridine, 4-thiouridine, cytidine, thymidine, 2'-deoxyguanosine, ribofuranosylthymine, a 2,2'-anhydroderivative, 2'-deoxycytidine, 2'-d
