83242-98-2

Upstream product

• 74-93-1 methylthiol 
• 139374-46-2 5,6-dihydroxy-3-methoxy-2-(1H)-pyridinethione 
• 139374-44-0 cis-4-hydroxy-3-methoxy-2-piperidinone 
• 139374-43-9 cis-3,4-dihydroxy-2-piperidinone 
• 139374-45-1 5,6-dihydroxy-3-methoxy-2(1H)-pyridinone 
• 6052-73-9 5,6-dihydro-2(1H)-pyridinone 

Relevant academic research and scientific papers

Syntheses of trans- and cis-3-Methoxy-4-methylthio-2-piperidinethiones. Previously Proposed Structures for Raphanusanins, Structural Revision, and Biological Activities of Their Congeners

Related to raphanusanins, light-induced growth inhibitors of radish seedlings, syntheses of trans- and cis-3-methoxy-4-methylthio-2-piperidinethiones provided the structural revision of the natural products.During syntheses of several piperidinethione derivatives, the dihydropyridinethione derivative was found to possess twentyfold stronger inhibitory activity than the natural products.

Syntheses of trans- and cis-3-methoxy-4-methylthio-2-piperidinethiones previously proposed for raphanusanins: Correct structures of raphanusanins

Trans- and cis-3-methoxy-4-methylthio-2-piperidinethiones previously proposed for raphanusanins as a light-induced growth inhibitor, have been synthesized starting from the known α,β-unsaturated lactam. However, the spectral data of the synthetic compounds are incompatible with those of natural ones. Thus, reexamination of 1H and 13C NMR spectra of the natural samples has led to correct structures for raphanusanins. The synthetic compounds also show a growth inhibitory activity.