83246-84-8Relevant academic research and scientific papers
5,6,7,8-Tetrahydroquinolines. Part 7. Synthesis of 8-Cyano-5,6,7,8-tetrahydroquinolines; Di-isopropylcyanamide, a New Reagent for Cyanation of Organometallics
Crossley, Roger,Shepherd, Robin G.
, p. 2479 - 2482 (2007/10/02)
Di-isopropylcyanamide (1) is an effective reagent for the conversion of 8-lithio-5,6,7,8-tetrahydroquinolines into 8-cyano-5,6,7,8-tetrahydroquinolines. 8,8-Dicyano derivatives are not formed.A convenient synthesis of the reagent from disodium cyanamide is described.
