83257-94-7Relevant academic research and scientific papers
SYNTHESIS OF NITRO AND AMINO DERIVATIVES OF THE MACROCYCLIC POLYETHER 2,3-BENZO-1,4,7,10,13,16-HEXAOXACYCLOOCTADEC-2-ENE
Abakumova, N. I.,Kolenko, I. K.,Kodess, M. I.
, p. 1305 - 1307 (2007/10/02)
Convenient methods were developed for the synthesis of 1,2-di(2-hydroxyethoxy)benzene, 1,2-di(2-hydroxyethoxy)-4-nitrobenzene, and 1,2-di(2-hydroxyethoxy)-4,6-dinitrobenzene - the intermediate products in the synthesis of nitro and amino derivatives of 2,3-benzo-1,4,7,10,13,16-hexaoxacyclodec-2-ene (benzo-18-crown-6).The effect of the nature of the solvent on the yield of mono- and dinitro derivatives of 1,2-di(2-hydroxyethoxy)benzene in the nitration of the latter was investigated.It was shown that benzo-18-crown-6 and dicyclohexyl-18-crown-6 have a catalytic effect on the yield of the products from O-alkylation of 1,2-dihydroxybenzene and its derivatives.
