83269-05-0Relevant articles and documents
1,2-dihydropyrido[3,4-b]pyrazines
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, (2008/06/13)
1,2-Dihydropyrido[3,4-b]pyrazines are provided which possess anticancer activity. The compounds have the structure: STR1 wherein Y is CH2 or N(CH3); R1 is a lower alkyl group; e.g., an alkyl group containing up to six carb
1,2-Dihydropyrido[3,4-b]pyrazines: Structure-activity relationships
Temple Jr.,Wheeler,Elliott,Rose,Comber,Montgomery
, p. 91 - 95 (2007/10/02)
Certain derivatives containing the 1,2-dihydropyrido[3,4-b]pyrazine (1-deaza-7,8-dihydropteridine) ring system are active against experimental neoplasms in mice. The mechanism of action of these agents has r539w1 =4-amino-1-deaza-7,8-dihydro-6-[(N-methyla