832714-46-2 Usage
Uses
APD 668 is a potent agonist of GPR119, a glucose-dependant insulinotropic receptor expressed in pancreatic β-cells and intestinal L-cells.
references
[1]. semple g, ren a, fioravanti b, et al. discovery of fused bicyclic agonists of the orphan g-protein coupled receptor gpr119 with in vivo activity in rodent models of glucose control. bioorg med chem lett, 2011, 21(10):3134-41.[2]. soga t, ohishi t, matsui t, et al. lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan g-protein-coupled receptor. biochem biophys res commun, 2005, 326(4):744-51. [3]. overton ha, babbs aj, doel sm, et al. deorphanization of a g protein coupled receptor for oleoylethanolamide and its use in the discovery of small molecule hypophagic agents. cell metab, 2006, 3(3):167-75.
Check Digit Verification of cas no
The CAS Registry Mumber 832714-46-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,3,2,7,1 and 4 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 832714-46:
(8*8)+(7*3)+(6*2)+(5*7)+(4*1)+(3*4)+(2*4)+(1*6)=162
162 % 10 = 2
So 832714-46-2 is a valid CAS Registry Number.
