832722-53-9

Upstream product

• 832722-36-8 N-[(1R)-2-methoxy-1-phenylethyl]-N-[(1R)-1-(trifluoromethyl)prop-2-enyl]amine 
• 832722-41-5 N-[(1R)-2-methoxy-1-phenylethyl]-N-[(1R)-1-(trifluoromethyl)prop-2-enyl]acetamide 

Downstream Products

• 1200084-76-9 (S)-methyl 2-{(2S,3R)-3-[(R)-2-methoxy-1-phenylethylamino]-4,4,4-trifluoro-2-hydroxybutylamino}propanoate 
• 1200085-02-4 (S)-ethyl 2-{(2S,3R)-3-[(R)-2-methoxy-1-phenylethylamino]-4,4,4-trifluoro-2-hydroxybutylamino}propanoate 
• 1200084-82-7 (S)-methyl 2-{(2S,3R)-3-[(R)-2-methoxy-1-phenylethylamino]-4,4,4-trifluoro-2-hydroxybutylamino}-4-(methylthio)butanoate 
• 1200085-00-2 (S)-ethyl 2-{(2S,3R)-3-[(R)-2-methoxy-1-phenylethylamino]-4,4,4-trifluoro-2-hydroxybutylamino}-4-(methylthio)butanoate 
• 1200084-84-9 (S)-dimethyl 2-{(2S,3R)-3-[(R)-2-methoxy-1-phenylethylamino]-4,4,4-trifluoro-2-hydroxybutylamino}succinate 
• 1200084-78-1 (S)-methyl 2-{(2S,3R)-3-[(R)-2-methoxy-1-phenylethylamino]-4,4,4-trifluoro-2-hydroxybutylamino}-3-phenylpropanoate 
• 1200084-98-5 (S)-ethyl 2-{(2S,3R)-3-[(R)-2-methoxy-1-phenylethylamino]-4,4,4-trifluoro-2-hydroxybutylamino}-3-phenylpropanoate 
• 1200084-92-9 (S)-benzyl 2-{(2S,3R)-3-[(R)-2-methoxy-1-phenylethylamino]-4,4,4-trifluoro-2-hydroxybutylamino}-3-phenylpropanoate 
• 1200084-80-5 (S)-methyl 2-{(2S,3R)-3-[(R)-2-methoxy-1-phenylethylamino]-4,4,4-trifluoro-2-hydroxybutylamino}-3-[4-(benzyloxy)phenyl]propanoate 
• 1200084-86-1 methyl N-((2S,3R)-4,4,4-trifluoro-2-hydroxy-3-{[(1R)-2-methoxy-1-phenylethyl]amino}butyl)-L-phenylalanyl-L-alaninate 
• 1200084-74-7 ethyl 2-{(2S,3R)-3-[(R)-2-methoxy-1-phenylethylamino]-4,4,4-trifluoro-2-hydroxybutylamino}acetate 

Relevant academic research and scientific papers

Synthesis of new trifluoromethylated hydroxyethylamine-based scaffolds

A very easy access to new trifluoromethyl-hydroxyethylamine (Tf-HEA) derivatives by epoxide ring opening with amino-containlng compounds, including aliphatic amines, aniline, aqueous ammonia, hydroxylamirie, hydrazine, amino acids and a dipeptide, is desc

Analogues of key precursors of aspartyl protease inhibitors: Synthesis of trifluoromethyl amino epoxides

(Chemical Equation Presented) The synthesis of the title compound is described through original and tailored synthetic protocols. The addition of vinylmagnesium bromide to CF3-N-aryl and N-alkyl aldimines was efficient and did not require an ac