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3',5'-di-O-acetyl-O6-benzyl-N2-[[[[4''-[(2''',3''',4'''-tri-O-acetyl-6'''-methyl-β-D-glucopyranuronosyl)oxy]-3''-nitrophenyl]methyl]oxy]carbonyl]-2'-deoxyguanosine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

832739-11-4

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832739-11-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 832739-11-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,3,2,7,3 and 9 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 832739-11:
(8*8)+(7*3)+(6*2)+(5*7)+(4*3)+(3*9)+(2*1)+(1*1)=174
174 % 10 = 4
So 832739-11-4 is a valid CAS Registry Number.

832739-11-4Downstream Products

832739-11-4Relevant academic research and scientific papers

β-Glucuronidase-cleavable prodrugs of O6-benzylguanine and O6-benzyl-2′-deoxyguanosine

Wei, Guangping,Loktionova, Natalia A.,Pegg, Anthony E.,Moschel, Robert C.

, p. 256 - 261 (2005)

Glucuronic acid linked prodrugs of O6-benzylguanine and O 6-benzyl-2′-deoxyguanosine were synthesized. The prodrugs were found to be quite stable at physiological pH and were more than 200-fold less active as inactivators of O6

BETA-GLUGURONIDASE CLEAVABLE PRODRUGS OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE INACTIVATORS

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Page/Page column 18, (2010/10/20)

Disclosed are prodrugs of inactivators of 06-alkylguanine-DNA alkyltransferase (AGT). The prodrugs are cleavable by the (3-glucuronidase enzyme, which is either administered to the patient or produced by necrotic tumor cells. The prodrugs are r

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