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1-(4-ethyl-phenyl)-4,4-difluoro-butane-1,3-dione is a chemical compound characterized by its molecular formula C12H14F2O2. It is a yellow crystalline solid at room temperature, known for its unique reactivity and chemical properties due to the presence of a 4-ethyl-phenyl group and a difluoro-butane-1,3-dione moiety in its structure. This di-ketone compound, with two carbonyl groups and a butane backbone, is widely recognized as a valuable building block in organic synthesis.

832741-19-2

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832741-19-2 Usage

Uses

Used in Pharmaceutical Synthesis:
1-(4-ethyl-phenyl)-4,4-difluoro-butane-1,3-dione is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique chemical properties and reactivity make it a promising candidate for the development of new medications with improved efficacy and reduced side effects.
Used in Agrochemical Synthesis:
In the agrochemical industry, 1-(4-ethyl-phenyl)-4,4-difluoro-butane-1,3-dione is utilized as a key intermediate in the production of pesticides and other agrochemicals. Its structural features contribute to the creation of compounds with enhanced performance and selectivity, benefiting agricultural practices and crop protection.
Used in Organic Synthesis:
1-(4-ethyl-phenyl)-4,4-difluoro-butane-1,3-dione is also employed as a versatile building block in organic synthesis across various industries. Its distinctive structure allows for the development of a wide range of organic compounds with diverse applications, from specialty chemicals to advanced materials.

Check Digit Verification of cas no

The CAS Registry Mumber 832741-19-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,3,2,7,4 and 1 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 832741-19:
(8*8)+(7*3)+(6*2)+(5*7)+(4*4)+(3*1)+(2*1)+(1*9)=162
162 % 10 = 2
So 832741-19-2 is a valid CAS Registry Number.

832741-19-2Downstream Products

832741-19-2Relevant academic research and scientific papers

Discovery of a potent, selective and orally active canine COX-2 inhibitor, 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine

Li, Jin,Lundy DeMello, Kristin M.,Cheng, Henry,Sakya, Subas M.,Bronk, Brian S.,Rafka, Robert J.,Jaynes, Burton H.,Ziegler, Carl B.,Kilroy, Carolyn,Mann, Donald W.,Nimz, Eric L.,Lynch, Michael P.,Haven, Michelle L.,Kolosko, Nicole L.,Minich, Martha L.,Li, Chao,Dutra, Jason K.,Rast, Bryson,Crosson, Rhonda M.,Morton, Barry J.,Kirk, Glen W.,Callaghan, Kathleen M.,Koss, David A.,Shavnya, Andrei,Lund, Lisa A.,Seibel, Scott B.,Petras, Carol F.,Silvia, Annette

, p. 95 - 98 (2007/10/03)

Structure-activity relationship (SAR) studies of 2-[3-di(and tri)fluoromethyl-5-arylpyrazol-1-yl]-5-methanesulfonylpyridine derivatives for canine COX enzymes are described. This led to the identification of 12a as a lead candidate for further progression. The in vitro and in vivo activity of 12a for the canine COX-2 enzyme as well as its in vivo efficacy and pharmacokinetic properties in dog are highlighted.

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