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3-Chloro-4-(trifluoromethoxy)benzaldehyde is an organic compound characterized by the presence of a chloro group at the 3-position and a trifluoromethoxy group at the 4-position on a benzene ring. It serves as a key intermediate in the synthesis of various organic compounds, particularly in the development of pharmaceuticals and agrochemicals.

83279-38-3

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83279-38-3 Usage

Uses

Used in Pharmaceutical Industry:
3-Chloro-4-(trifluoromethoxy)benzaldehyde is used as a synthetic intermediate for the development of γ-Aminobutyrate-A (GABA-A) receptor modulators. These modulators are crucial in the treatment of neurological disorders and conditions such as anxiety, epilepsy, and insomnia.
Used in Organic Synthesis:
In the field of organic synthesis, 3-chloro-4-(trifluoromethoxy)benzaldehyde is utilized as a building block for the synthesis of 3-aryl-1-(arylsulfonyl)-1,4,5,6-tetrahydropyridazines. These compounds exhibit potential applications in medicinal chemistry and drug discovery, contributing to the advancement of novel therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 83279-38-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,2,7 and 9 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 83279-38:
(7*8)+(6*3)+(5*2)+(4*7)+(3*9)+(2*3)+(1*8)=153
153 % 10 = 3
So 83279-38-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H4ClF3O/c9-7-3-5(4-13)1-2-6(7)8(10,11)12/h1-4H

83279-38-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Chloro-4-(trifluoromethyl)benzaldehyde

1.2 Other means of identification

Product number -
Other names 3-CHLORO-4-(TRIFLUOROMETHOXY)BENZALDEHYDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:83279-38-3 SDS

83279-38-3Relevant academic research and scientific papers

TYK2 INHIBITORS AND USES THEREOF

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Paragraph 00536, (2020/09/27)

Described herein are compounds that are useful in treating a TYK2-mediated disorder. In some embodiments, the TYK2-mediated disorder is an autoimmune disorder, an inflammatory disorder, a proliferative disorder, an endocrine disorder, a neurological disorder, or a disorder associated with transplantation.

TRPV1 ANTAGONISTS

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Page/Page column 30-32, (2009/05/28)

Compounds of formula (I) wherein R1, R2, R4, and W are defined in the description are TRPV 1 antagonists with CNS penetration. Compositions comprising such compounds and methods for treating conditions and disorders using

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