83279-38-3 Usage
Uses
Used in Pharmaceutical Industry:
3-Chloro-4-(trifluoromethoxy)benzaldehyde is used as a synthetic intermediate for the development of γ-Aminobutyrate-A (GABA-A) receptor modulators. These modulators are crucial in the treatment of neurological disorders and conditions such as anxiety, epilepsy, and insomnia.
Used in Organic Synthesis:
In the field of organic synthesis, 3-chloro-4-(trifluoromethoxy)benzaldehyde is utilized as a building block for the synthesis of 3-aryl-1-(arylsulfonyl)-1,4,5,6-tetrahydropyridazines. These compounds exhibit potential applications in medicinal chemistry and drug discovery, contributing to the advancement of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 83279-38-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,2,7 and 9 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 83279-38:
(7*8)+(6*3)+(5*2)+(4*7)+(3*9)+(2*3)+(1*8)=153
153 % 10 = 3
So 83279-38-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H4ClF3O/c9-7-3-5(4-13)1-2-6(7)8(10,11)12/h1-4H
83279-38-3Relevant academic research and scientific papers
TYK2 INHIBITORS AND USES THEREOF
-
Paragraph 00536, (2020/09/27)
Described herein are compounds that are useful in treating a TYK2-mediated disorder. In some embodiments, the TYK2-mediated disorder is an autoimmune disorder, an inflammatory disorder, a proliferative disorder, an endocrine disorder, a neurological disorder, or a disorder associated with transplantation.
TRPV1 ANTAGONISTS
-
Page/Page column 30-32, (2009/05/28)
Compounds of formula (I) wherein R1, R2, R4, and W are defined in the description are TRPV 1 antagonists with CNS penetration. Compositions comprising such compounds and methods for treating conditions and disorders using