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Methyl 4-[2-Hydroxy-3-(isopropylamino)propoxy]phenylacetate hydrochloride is a chemical compound that belongs to the class of aryloxypropanolamine andrenergic antagonists. It is a derivative of Metoprolol, a β1 selective adrenergic antagonist, and is characterized by the presence of a hydroxypropoxy group and an isopropylaminopropoxy group attached to a phenylacetate moiety. methyl 4-[2-Hydroxy-3-(isopropylamino)propoxy]phenylacetate hydrochloride exhibits weak acidic properties and is soluble in water due to the presence of the hydrochloride salt.

83281-59-8

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83281-59-8 Usage

Uses

Used in Pharmaceutical Industry:
Methyl 4-[2-Hydroxy-3-(isopropylamino)propoxy]phenylacetate hydrochloride is used as a pharmaceutical agent for the treatment of various cardiovascular disorders. It functions as a β1 selective adrenergic antagonist, which helps in reducing heart rate and blood pressure, making it a potential candidate for the management of conditions such as hypertension, angina, and arrhythmias.
Used in Drug Development:
As a derivative of Metoprolol, methyl 4-[2-Hydroxy-3-(isopropylamino)propoxy]phenylacetate hydrochloride can be further investigated and optimized for improved pharmacological properties, such as enhanced selectivity, potency, and reduced side effects. This makes it a valuable compound for drug development and the discovery of novel therapeutic agents targeting cardiovascular diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 83281-59-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,2,8 and 1 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 83281-59:
(7*8)+(6*3)+(5*2)+(4*8)+(3*1)+(2*5)+(1*9)=138
138 % 10 = 8
So 83281-59-8 is a valid CAS Registry Number.

83281-59-8Downstream Products

83281-59-8Relevant academic research and scientific papers

METHOD FOR TREATMENT OR PROPHYLAXIS OF CARDIAC DISORDERS

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, (2008/06/13)

A method for the treatment of prophylaxis of cardiac disorders in a mammal, comprising administering to such mammal a short-acting β-blocking compound of the formula: STR1 wherein R may be lower alkyl, aryl, or aralkyl; n may be an integer from 0 to about 10; x may be an integer from 1 to 3; Ar may be substituted or unsubstituted aromatic; R. sub.1 may be lower alkyl, or aralkyl; and pharmaceutically accepted salts thereof. Novel compounds possessing short-acting β-adrenergic blocking activity are also disclosed.

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