83287-28-9Relevant articles and documents
Nickel-BINAP catalyzed enantioselective α-arylation of α-substituted γ-butyrolactones
Spielvogel, Dirk J.,Buchwald, Stephen L.
, p. 3500 - 3501 (2007/10/03)
A Ni(0)-BINAP system is utilized for the highly enantioselective α-arylation of α-substituted γ-butyrolactones with aryl chlorides and bromides. α-Quaternization is achieved in moderate to excellent yields. Furthermore, the rate accelerating effect caused by the addition of Zn(II) salts is investigated. Copyright