83304-59-0Relevant academic research and scientific papers
Azetidinone-4-carboxylate containing a protected 3-acetyl group and process for their preparation
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, (2008/06/13)
The invention relates to new heterocyclic compounds containing a protected C-acetyl group. More particularly, the invention concerns new compounds of the Formula (V) STR1 wherein R is a group suitable for the protection of amides; Z is alkyl; and Y1
Beta-lactam compounds containing a C-acetal group and process for their preparation
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, (2008/06/13)
The invention relates to new heterocyclic compounds containing a C-acetyl group and a process for their preparation. More particularly, the invention concerns new compounds of the formula (III). STR1 in which R is a protecting group suitable for temporary
Beta-lactam compounds containing a protected C-acetyl group, process for their preparation and pharmaceutical compositions containing them
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, (2008/06/13)
The invention relates to new heterocyclic compounds containing a protected C-acetyl group. More particulary, the invention concerns new compounds of the formula (VI) STR1 wherein R1 is hydrogen or a group suitable for a temporary protection or amides, X is hydroxyl, halogen, cyano or an --O--SO2 --R2 group, in which R2 is lower alkyl or aryl, Y1 and Y2 together form a group suitable for a temporary protection of a keto group. The new compounds possess anaphylactic properties and are valuable intermediates of thienamycin synthesis. Their preparation and the new intermediates obtained during their preparation are also within the scope of the invention.
Heterocyclic compounds containing an alkoxycarbonyl and a substituted methyl group
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, (2008/06/13)
The invention relates to new heterocyclic compound containing an alkoxycarbonyl and a substituted methyl group a process for the preparation of these and analogeous compound and pharmaceutical compositions containing them. More particularly, the invention concerns compounds of the general formula (IVa) STR1 wherein R' is hydrogen, 2-ethoxycarbonylethyl, aryl or a group suitable for a temporary protection of amides and Y' represents a group of the formula --COOZ or --CH2 M, in which Z is lower alkyl and M is hydroxyl, halogen, cyano or a group of the formula --O--SO2 R2, in which R2 is lower alkyl or aryl, with the proviso that if R' is phenyl, Y' cannot stand for the group --COOC2 H5. The invention further relates to a process for the preparation of compounds of the general formula (IV) STR2 in which R and Y are identical with R' and Y', respectively, except the proviso. According to a further aspect of the invention there are provided pharmaceutical compositions, first of all with antihypoxic activity, comprising compounds of the general formula (IVa) as active ingredient.
