83320-98-3Relevant academic research and scientific papers
REGIOSELECTIVE OXIDATION OF INTERNAL OLEFINS BEARING NEIGHBORING OXYGEN FUNCTIONS BY MEANS OF PALLADIUM CATALYSTS. PREPARATION OF β-ALKOXY OR ACETOXY KETONES FROM ALLYL AND HOMOALLYL ETHERS OR ESTERS
Tsuji, Jiro,Nagashima, Hideo,Hori, Kimihiko
, p. 2679 - 2682 (1982)
A new preparative method of β- and γ-alkoxy (acetoxy) ketones, which are important precursors of vinyl ketones and 1,4-diketones, respectively, is presented.With PdCl2/CuCl/O2 or PdCl2/p-benzoquinone catalyst system, internal olefins bearing allylic alkoxy or acetoxy group underwent regioselective oxidation to form the corresponding β-alkoxy or β-acetoxy ketones.Similarly, γ-acetoxy ketones were obtained from homoallyl acetates having internal olefins with high regioselectivity.
