83327-30-4Relevant articles and documents
Diversity oriented approach to polycyclic compounds through the diels-alder reaction and the Suzuki coupling
Kotha, Sambasivarao,Misra, Shilpi,Srinivas, Venu
, p. 4052 - 4062 (2012)
A diversity oriented strategy has been demonstrated to deliver small "drug like" molecules using alkylation, Diels-Alder reaction, and Suzuki-Miyaura cross-coupling as key steps. This methodology allows access a wide range of molecules using simple scaffolds such as indanes, tetralins and tetrahydroisoquinolines, which can enhance the chemical space for potential therapeutic molecules.