83329-73-1 Usage
Uses
Used in Anticancer Applications:
Hygrolidin is used as a tumor growth and cyclin-dependent kinase (cdk) inhibitor for its ability to inhibit the proliferation of various cancer cell lines, such as DLD-1 colon cancer, LNCaP prostate cancer, and K562 leukemia cells. It induces the expression and levels of p21 in DLD-1 cells, leading to cell accumulation in the G1 and S phases without inducing apoptosis.
Used in Antifungal Applications:
Hygrolidin is used as an antifungal agent for its activity against Valsa ceratosperma, the pathogen of apple canker disease.
Used in Antiparasitic Applications:
Hygrolidin is used as an antiparasitic agent for its activity against Trypanosoma cruzi, Leishmania donovani, and Trypanosoma brucei, which are responsible for Chagas disease, leishmaniasis, and African trypanosomiasis, respectively.
However, it is important to note that Hygrolidin also exhibits cytotoxicity in HepG2 cells, which may limit its therapeutic potential in some applications. Further research and development of drug delivery systems may be necessary to enhance its efficacy and reduce toxicity.
Check Digit Verification of cas no
The CAS Registry Mumber 83329-73-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,3,2 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 83329-73:
(7*8)+(6*3)+(5*3)+(4*2)+(3*9)+(2*7)+(1*3)=141
141 % 10 = 1
So 83329-73-1 is a valid CAS Registry Number.
