83341-75-7

Basic information

• Product Name: 2-Cyclohexyl-3,4,5,6-tetrahydro-t-6-(4-methoxyphenyl)-2H-1,2-oxazin-r-5-carbonsaeure-methylester
• CAS NO: 83341-75-7
• Molecular Weight: 333.428
• Mol File: 83341-75-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Cyclohexyl-3,4,5,6-tetrahydro-t-6-(4-methoxyphenyl)-2H-1,2-oxazin-r-5-carbonsaeure-methylester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexyl-3,4,5,6-tetrahydro-t-6-(4-methoxyphenyl)-2H-1,2-oxazin-r-5-carbonsaeure-methylester(83341-75-7)
• EPA Substance Registry System: 2-Cyclohexyl-3,4,5,6-tetrahydro-t-6-(4-methoxyphenyl)-2H-1,2-oxazin-r-5-carbonsaeure-methylester(83341-75-7)

Safety Data

• Hazardous Substances Data: 83341-75-7(Hazardous Substances Data)

Upstream product

• 3901-07-3 3-(4-methoxy-phenyl)acrylic acid methyl ester 
• 37898-41-2 N-(2-Chlorethyliden)cyclohexylamin-N-oxid 

Relevant articles and documents

Cycloaddition Reactions of N-(2-Chloroethylidene)cyclohexylamine N-Oxide with Cinnamate Derivatives

Cyloaddition reactions of N-(2-chloroethylidene)cyclohexylamine N-oxide (2) with the olefins 10a-f at 0 deg C in the presence of AgBF4 in 1,2-dichloroethane as solvent furnish the reactive iminium salts 11a-f in a regio and stereoselective manner.Subsequent reaction of 11a-f with KCN or NaBH4 in water yields the substituted 1,2-oxazine derivatives 12a-b and 13a-f, respectively.Reaction of 10b with 2 in the presence of AgBF4 in liquid SO2 at -15 deg C followed by KCN/H2O work-up causes cleavage of the ester group.