83356-17-6

Basic information

• Product Name: 5-(benzoylamino)-4-oxo-6-phenylhexanoic acid
• CAS NO: 83356-17-6
• Molecular Formula: C₁₉H₁₉NO₄
• Molecular Weight: 325.3585
• Mol File: 83356-17-6.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 603.6°C at 760 mmHg
• Flash Point: 318.9°C
• Density: 1.227g/cm³
• Vapor Pressure: 2.01E-15mmHg at 25°C
• Refractive Index: 1.586
• CAS DataBase Reference: 5-(benzoylamino)-4-oxo-6-phenylhexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(benzoylamino)-4-oxo-6-phenylhexanoic acid(83356-17-6)
• EPA Substance Registry System: 5-(benzoylamino)-4-oxo-6-phenylhexanoic acid(83356-17-6)

Safety Data

• Hazardous Substances Data: 83356-17-6(Hazardous Substances Data)

Upstream product

• 83646-23-5 2-((S)-1-Benzyl-2-oxo-hex-5-enyl)-isoindole-1,3-dione 
• 74075-26-6 2-(3-oxo-5-phenyl-(4S)-4-phthalimidopentyl)-1,3-dioxolane 
• 74075-29-9 2-<2-(1,3-dioxolan-2-yl)ethyl>-2-<(1S)-1-benzamido-2-phenylethyl>-1,3-dioxolane 
• 74075-28-8 (S)-1-[2-(2-[1,3]Dioxolan-2-yl-ethyl)-[1,3]dioxolan-2-yl]-2-phenyl-ethylamine 
• 33861-65-3 N-phthaloyl-L-phenylalanine-2-mercaptopyridyl thioester 
• 910316-83-5 ethyl (5S)-5-[(N-benzoyl)amino]-4-oxo-6-phenyl-hexanoate 
• 83646-28-0 N-[(S)-1-(2-But-3-enyl-[1,3]dioxolan-2-yl)-2-phenyl-ethyl]-benzamide 
• 29670-63-1 N-benzoyl-2-phenylglycine 
• 83084-67-7 2-Phenyl-4-benzyl-4-β-carbomethoxypropionyloxazolone 
• 5874-61-3 4-benzyl-2-phenyl-2-oxazolin-5-one 
• 77982-73-1 (R,S)-5-benzoylamino-4-oxo-6-phenylhexanoic acid methyl ester 
• 74075-27-7 2-<2-(1,3-dioxolan-2-yl)ethyl>-2-<(1S)-1-phthalimido-2-phenylethyl>-1,3-dioxolane 
• 74075-30-2 3-[2-((S)-1-Benzoylamino-2-phenyl-ethyl)-[1,3]dioxolan-2-yl]-propionic acid 

Relevant articles and documents

Angiotensin I-converting enzyme (ace) inhibitors

This invention relates to a process for the synthesis of ketomethylene derivatives of the tripeptide Phe-Gly-Pro (“keto-ACE”, compound 5a) and analogues thereof. The synthesis process proceeds via an α,β-unsaturated keto intermediate. A key feature of the process involves a Horner-Emmons olefination of the, -unsaturated keto-phosphonate with ethyl glyoxylate. Keto-ACE analogues produced by the process of the invention display C-domain selectivity.

Ketomethylene pseudopeptide analogues of substance P: Synthesis and biological activity

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SYNTHESIS OF KETOMETHYLENE ANALOGS OF DIPEPTIDES

A convenient method of synthesizing ketomethylene dipeptides by using homoallylic Grignard reagents as amino acid analog synthons is described.