83375-61-5Relevant articles and documents
A Convenient Synthesis of 4-Unsubstituted β-Lactams
Overman, Larry E.,Osawa, Tatsushi
, p. 1698 - 1701 (2007/10/02)
The reaction of lithium ester enolates with N-(cyanomethyl)amines affords 4-unsubstituted β-lactams in good yields, see eq 1.The N-1 substituent can be varied widely, as can the C-3 substituents, which can be H, alkyl, SPh, NH2, or NHCOR.The preparation o
NOVEL STEREOSELECTIVE SYNTHESIS OF β-LACTAMS VIA EPISULFONIUM ION INTERMEDIATE
Ihara, Masataka,Fukumoto, Keiichiro
, p. 1435 - 1438 (2007/10/02)
A number of monocyclic β-lactams were synthesized by addition of benzenesulfonyl chloride to α,β-unsaturated olefins followed by base treatment in the presence of a phase transfer catelyst.The cyclization proceeds in a stereoselective manner most probably
