83386-35-0 Usage
Uses
Used in Pharmaceutical Industry:
N-[[5-(2-fluorophenyl)-2,3-dihydro-1-methyl-1H-1,4-benzodiazepin-2-yl]methyl]thiophene-3-carboxamide is used as a potential candidate for the development of new drugs targeting the central nervous system. Its benzodiazepine nature suggests it may be effective for conditions requiring sedation, sleep induction, anxiety reduction, and muscle relaxation. The presence of the fluorophenyl group could enhance its activity at serotonin receptors, potentially broadening its therapeutic applications to include treatment of mood disorders and other conditions influenced by serotonin levels.
Used in Research and Development:
In the field of medicinal chemistry, N-[[5-(2-fluorophenyl)-2,3-dihydro-1-methyl-1H-1,4-benzodiazepin-2-yl]methyl]thiophene-3-carboxamide serves as a valuable compound for research into the structure-activity relationships of benzodiazepines and their derivatives. It can be used to explore the impact of specific structural modifications on the pharmacological profile of these compounds, potentially leading to the discovery of more effective and safer drugs.
Used in Drug Design and Optimization:
N-[[5-(2-fluorophenyl)-2,3-dihydro-1-methyl-1H-1,4-benzodiazepin-2-yl]methyl]thiophene-3-carboxamide is utilized in the process of drug design and optimization to create novel therapeutic agents with improved pharmacokinetic and pharmacodynamic properties. Its unique structure allows for the investigation of how different functional groups and molecular modifications can influence the compound's affinity, selectivity, and efficacy at specific biological targets, such as GABA receptors or serotonin receptors.
Check Digit Verification of cas no
The CAS Registry Mumber 83386-35-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,3,8 and 6 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 83386-35:
(7*8)+(6*3)+(5*3)+(4*8)+(3*6)+(2*3)+(1*5)=150
150 % 10 = 0
So 83386-35-0 is a valid CAS Registry Number.
InChI:InChI=1/C22H20FN3OS/c1-26-16(13-25-22(27)15-10-11-28-14-15)12-24-21(17-6-2-4-8-19(17)23)18-7-3-5-9-20(18)26/h2-11,14,16H,12-13H2,1H3,(H,25,27)
83386-35-0Relevant academic research and scientific papers
2-ACYLAMINOMETHYL-1,4-BENZODIAZEPINE DERIVATIVES AS CCK-ANTAGONISTS
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, (2008/06/13)
A method of antagonizing the function of cholecystokinins in a disease state in mammals, especially in humans, which comprises administering a pharmaceutically-effective amount of certain 2-acylaminomethyl-1,4-benzodiazepine derivatives or their salts, alone or with a pharmaceutical carrier, with or without an adjuvant.
