83395-21-5

Basic information

• Product Name: Ridazolol
• Synonyms: Ridazolol;4-Chloro-5-[[2-[[3-(2-chlorophenoxy)-2-hydroxypropyl]amino]ethyl]amino]pyridazin-3(2H)-one;CAS-413;4-chloro-5-[[2-[[3-(2-chlorophenoxy)-2-hydroxypropyl]amino]ethyl]amino]-3(2H)-Pyridazinone
• CAS NO: 83395-21-5
• Molecular Formula: C15H18Cl2N4O3
• Molecular Weight: 373.238
• Mol File: 83395-21-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.46g/cm³
• Refractive Index: 1.631
• CAS DataBase Reference: Ridazolol(CAS DataBase Reference)
• NIST Chemistry Reference: Ridazolol(83395-21-5)
• EPA Substance Registry System: Ridazolol(83395-21-5)

Safety Data

• Hazardous Substances Data: 83395-21-5(Hazardous Substances Data)

Usage

Uses

Ridazolol is a potent beta-adrenergic antagonist with moderate alpha-adrenolytic activity.

InChI:InChI=1/C15H18Cl2N4O3/c16-11-3-1-2-4-13(11)24-9-10(22)7-18-5-6-19-12-8-20-21-15(23)14(12)17/h1-4,8,10,18,22H,5-7,9H2,(H2,19,21,23)

Relevant articles and documents

N-phenoxypropanol-N'-pyridazinyl ethylendiamines as β-receptor blockers

Basically-substituted pyridazines of the formula: STR1 wherein R1, R2 and R3, independently of one another, denote hydrogen, halogen, hydroxyl, nitro, trifluoromethyl, alkyl, alkoxyalkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, phenyl, alkoxy, hydroxyalkoxy, alkoxy-alkoxy, alkenyloxy, alkynyloxy, cycloalkoxy, phenalkoxy, alkanoyl, alkanoylamino and --NH--CO--R9, R9 representing morpholino, piperidino or 1-pyrrolididinyl, or an optionally substituted ureido radical, R4 denotes hydrogen or lower alkyl and W denotes hydrogen, chlorine or bromine; and the acid-addition salts thereof are useful alone or in pharmaceutical preparations for treating cardiac complaints, circulatory complaints and high blood pressure. Several methods for preparing the basically-substituted pyridazines are also provided.