83395-38-4

Basic information

• Product Name: 1H-Imidazole-1-carboxylicacid,2-propynylester(9CI)
• Synonyms: 1H-Imidazole-1-carboxylicacid,2-propynylester(9CI);1H-Imidazole-1-carboxylic acid, 2-propyn-1-yl ester;PImC;Propargyl 1H-imidazole-1-carboxylate;Propargyl imidazolecarbamate;Propargyl 1H-imidazole-1-carboxylate 95%
• CAS NO: 83395-38-4
• Molecular Formula: C₇H₆N₂O₂
• Molecular Weight: 150.13
• Product Categories: CARBOXYLICESTER
• Mol File: 83395-38-4.mol

Chemical Properties

• Melting Point: 45-50°C
• Boiling Point: 255.5±42.0 °C(Predicted)
• Flash Point: >110℃
• Appearance: /
• Density: 1.11±0.1 g/cm3(Predicted)
• Vapor Pressure: 0.1-1Pa at 20-40℃
• Storage Temp.: 2-8°C
• PKA: 3.01±0.10(Predicted)
• CAS DataBase Reference: 1H-Imidazole-1-carboxylicacid,2-propynylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole-1-carboxylicacid,2-propynylester(9CI)(83395-38-4)
• EPA Substance Registry System: 1H-Imidazole-1-carboxylicacid,2-propynylester(9CI)(83395-38-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• Hazardous Substances Data: 83395-38-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
1H-Imidazole-1-carboxylic acid, 2-propynyl ester (9CI) is utilized as a research compound for its potential anti-inflammatory, anti-fungal, and anti-tumor properties. It is studied for its capacity to modulate various biological processes and pathways, offering therapeutic benefits in different medical conditions.
Used in Organic Synthesis:
In the field of organic synthesis, 1H-Imidazole-1-carboxylic acid, 2-propynyl ester (9CI) serves as a key building block for the synthesis of a variety of pharmaceutical drugs and bioactive compounds. Its unique structure and functional groups make it a versatile intermediate in the development of new chemical entities with potential therapeutic applications.
Used in Neurodegenerative Disease Treatment:
1H-Imidazole-1-carboxylic acid, 2-propynyl ester (9CI) is explored for its role in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's. Its potential to influence neuroprotective mechanisms and mitigate disease progression makes it a promising candidate for further research and development in this area.

Upstream product

• 288-32-4 1H-imidazole 
• 35718-08-2 propargyl chloroformate 

Downstream Products

• 90705-89-8 prop-2-yn-1-yl 2-(4-bromophenyl)acetate 

Relevant articles and documents

Facile synthesis of β-cyclodextrin-dextran polymers by "click" chemistry

Three series of novel water-soluble β-cyclodextrin-dextran polymers have been prepared by "click" chemistry. The polymers were synthesized from alkyne-modified dextrans (AMDs) onto which mono-6-O-deoxy-monoazido- βCD (N3βCD) was grafted by a copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC). The polymers have been characterized by NMR spectroscopy and size exclusion chromatography (SEC). The binding properties have been characterized by isothermal titration calorimetry (ITC) and show excellent accessibility of the βCDs.